COVID-19 Forum, Information, Studies, Treatments

COVID-19 Coronavirus => Are Vaccines the Panacea for COVID-19? How can we know what we can't know? => Topic started by: admin on August 27, 2021, 02:16:47 PM

Title: Comparable viral loads reported in vaxxed and unvaxxed patients, 251x AB strains
Post by: admin on August 27, 2021, 02:16:47 PM
https://childrenshealthdefense.org/defender/vaccinated-healthcare-workers-threat-unvaccinated-patients-co-workers/

"Updated 08/23/21
Study: Fully Vaccinated Healthcare Workers Carry 251 Times Viral Load, Pose Threat to Unvaccinated Patients, Co-Workers

A preprint paper by the prestigious Oxford University Clinical Research Group, published Aug. 10 in The Lancet, found vaccinated individuals carry 251 times the load of COVID-19 viruses in their nostrils compared to the unvaccinated. ["unvaccinated" meaning a comparison of Delta viral loads of today compared to the viral loads of the A/B strains in spring of 2020 prior to the vaccines]

By Peter A. McCullough, M.D., MPH

A groundbreaking preprint paper (https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3897733) by the prestigious Oxford University Clinical Research Group, published Aug. 10 in The Lancet, includes alarming findings devastating to the COVID vaccine rollout.

The study found vaccinated individuals carry 251 times the load of COVID-19 viruses in their nostrils compared to the unvaccinated. [again "unvaccinated" meaning a comparison of Delta viral loads of today compared to the viral loads of the A/B strains in spring of 2020 prior to the vaccines]

While moderating the symptoms of infection, the jab allows vaccinated individuals to carry unusually high viral loads without becoming ill at first, potentially transforming them into presymptomatic superspreaders.

This phenomenon may be the source of the shocking post-vaccination surges in heavily vaccinated populations globally.


The paper’s authors, Chau et al, demonstrated widespread vaccine failure and transmission under tightly controlled circumstances in a hospital lockdown in Ho Chi Minh City, Viet Nam.

The scientists studied healthcare workers who were unable to leave the hospital for two weeks. The data showed that fully vaccinated workers — about two months after injection with the Oxford/AstraZeneca (https://childrenshealthdefense.org/defender/deaths-johnson-johnson-astrazeneca-vaccines-strokes-young-adults/) COVID-19 vaccine (AZD1222) — acquired, carried and presumably transmitted the Delta variant to their vaccinated colleagues.

They almost certainly also passed the Delta infection to susceptible unvaccinated people
, including their patients. Sequencing of strains confirmed the workers transmitted SARS-CoV-2 to one another.

This is consistent with the observations in the U.S. from Farinholt and colleagues (https://www.medrxiv.org/content/10.1101/2021.06.28.21258780v1.full.pdf), and congruent with comments (https://www.cnn.com/2021/08/05/health/us-coronavirus-thursday/index.html) by the director of the Centers for Disease Control and Prevention conceding COVID-19 vaccines have failed to stop transmission of SARS-CoV-2.   

On Feb. 11, the World Health Organization indicated (https://www.who.int/news-room/feature-stories/detail/the-oxford-astrazeneca-covid-19-vaccine-what-you-need-to-know) the AZD1222 vaccine efficacy of 63.09% against the development of symptomatic SARS-CoV-2 infection. The conclusions of the Chau paper support the warnings by leading medical experts that the partial, non-sterilizing immunity from the three notoriously “leaky” COVID-19 vaccines allow carriage of 251 times the viral load of SARS-CoV-2 as compared to samples from the pre-vaccination era in 2020.

Thus, we have a key piece to the puzzle explaining why the Delta outbreak is so formidable — fully vaccinated are participating as COVID-19 patients and acting as powerful Typhoid Mary-style super-spreaders of the infection.

Vaccinated individuals are blasting out concentrated viral explosions into their communities and fueling new COVID surges. Vaccinated healthcare workers are almost certainly infecting their coworkers and patients, causing horrendous collateral damage.


Continued vaccination will only make this problem worse, particularly among frontline doctors and nurses workers who are caring for vulnerable patients.

Health systems should drop vaccine mandates immediately, take stock of COVID-19 recovered workers who are robustly immune to Delta and consider the ramifications of their current vaccinated healthcare workers as potential threats to high risk patients and coworkers.

CLARIFICATION: The comparison of viral load between vaccinated and unvaccinated (pre-vaccine era) as reported in the Chau et al. 2021 Lancet preprint is between two different variants of SARS-CoV-2. Dr. McCullough states directly that samples were compared to those “from the pre-vaccination era of 2020.” Thus, differences between these two groups aren’t a result of vaccination status alone. The authors of the Chau et al. 2021 study in their rebuttal (https://www.covid-19forum.org/index.php?topic=1004.msg1850#msg1850) to our piece point out another preprint (Li et al. 2021) which reported a difference in viral load of ~1000 between patients infected with the Delta variant and patients infected with A/B. However, the vaccination status of the Delta variant patients in this preprint is not reported. Thus, no one here has done a direct comparison between unvaccinated Delta patients and unvaccinated A/B patients to determine the true difference in viral load. In two additional preprint scientific publications (Riemersma et al. 2021, Chia et al. 2021), comparable viral loads of the Delta variant of SARS-CoV-2 are reported among vaccinated and unvaccinated patients. However, this itself is an indictment of vaccine efficacy as both vaccinated and unvaccinated individuals possess the ability to spread the Delta variant. Simply stated, COVID vaccines have failed to stop transmission of SARS-CoV-2.

The views and opinions expressed in this article are those of the authors and do not necessarily reflect the views of Children's Health Defense.
_________________________________

"The internal CDC presentation concluded that, "breakthrough infections may be as transmissible as unvaccinated cases."
"While the CDC's findings indicate that vaccinated people who get infected with the delta variant may be able to spread the virus as easily as unvaccinated individuals, vaccines have been shown to protect the vast majority of breakthrough infections from serious illness, hospitalization and death."
Title: Re: Scientists:Fully vaccinated carry 251 times the Covid viral load as unvaccinated
Post by: admin on August 27, 2021, 02:24:42 PM
Rebuttal from study authors:
http://www.oucru.org/our-preprint-article-transmission-of-sars-cov-2-delta-variant-among-vaccinated-healthcare-workers-vietnam/

"Our preprint article “Transmission of SARS-CoV-2 Delta Variant Among Vaccinated Healthcare Workers, Vietnam”

It has come to our attention that a recent post from the Children’s Health Defense on 23rd August 2021 shared the false claim that our paper demonstrated “vaccinated individuals carry 251 times the load of COVID-19 viruses in their nostrils compared to the unvaccinated”.

SARS-CoV-2 Delta variant infection is associated with high viral loads, which has been demonstrated in recent studies from various countries (including China (ref#1), Singapore (ref#2), the UK (ref#3), and the US (ref#4&5)). The study from China showed that viral loads in people infected with the Delta variant were 1000 times higher than those infected with the 19A/19B strains detected in China in early 2020. Additionally, the studies from the US, the UK and Singapore demonstrated that vaccinated and unvaccinated individuals infected with SARS-CoV-2 Delta variant carried the same amounts of the virus in their respiratory tracts, with a faster viral clearance rate observed in vaccinated people (according to the study from Singapore).

In our study (https://ssrn.com/abstract=3897733), we compared viral loads (inferred from PCR Ct values) from cases infected with the original SARS-CoV-2 strains detected in Vietnam between March and April 2020 (herein referred to original strains) with those from fully vaccinated healthcare workers infected with SARS-CoV-2 Delta variant.

Similar to data from the aforementioned studies, we showed that Delta variant infections in fully vaccinated healthcare workers were associated with high viral loads, and indeed were 250 times higher than those in people infected with the original strains. The differences in viral load were driven by the ability of the Delta variant to cause higher viral loads; they had nothing to do with the vaccination status of the infected individual. Thus the claim that vaccinated individuals carry 251 times the loads of SARS-CoV-2 in their respiratory tract compared to the unvaccinated people is a misrepresentation of the data.

There is overwhelming evidence for the effectiveness of vaccines in preventing severe disease and death from COVID-19. Our study provides no evidence to the contrary. We strongly endorse vaccination as a critical tool against COVID-19 and the terrible consequences of the pandemic.

Nguyen Van Vinh Chau, MD, PhD – Director of Hospital for Tropical Diseases, Ho Chi Minh City

Professor Guy Thwaites, MD, PhD  – Director of OUCRU

Le Van Tan, PhD – Head of Emerging Infections Group, OUCRU
References

1. Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant, https://www.medrxiv.org/content/10.1101/2021.07.07.21260122v2.full.pdf+html

2. Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine-breakthrough infections: a multi-center cohort study, https://www.medrxiv.org/content/10.1101/2021.07.28.21261295v1

3. Impact of Delta on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK, https://www.medrxiv.org/content/10.1101/2021.08.18.21262237v1

4. Shedding of Infectious SARS-CoV-2 Despite Vaccination, https://www.medrxiv.org/content/10.1101/2021.07.31.21261387v4.full.pdf+html

5. Outbreak of SARS-CoV-2 Infections, Including COVID-19 Vaccine Breakthrough Infections, Associated with Large Public Gatherings — Barnstable County, Massachusetts, July 202, https://www.cdc.gov/mmwr/volumes/70/wr/mm7031e2.htm "
Title: Re: Scientists: Fully vaccinated carry 251 times the delta Covid viral load as alpha
Post by: admin on September 01, 2021, 02:59:54 PM
Combine that with Big Pharma having created hundreds of millions of these asymptomatic COVID Typhoid Marys - so far.
https://www.covid-19forum.org/index.php?topic=948.0