Author Topic: Ivermectin treatment is a ‘real killer of coronavirus’ - a "wonder drug"  (Read 11384 times)

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Please read the important disclaimer at the following link before proceeding further on this page. The administrator of this forum is not a doctor nor licensed or experienced in any aspect of the health care industry.
https://www.covid-19forum.org/index.php?topic=227.0

[edit add 12-18-23]

[end edit]

Government propagandists have succeeded in making some people that don't bother to investigate, afraid to take ivermectin, even though its consumption has averaged 15 fatalities per year for decades.
Yet some of these same folks don't think twice about taking Tylenol even though:
"Each year, approximately 500 fatalities and 50,000 emergency department admissions in the United States are linked to acetaminophen.[23] In 2021, US poison control centers recorded over 80,000 cases. Acetaminophen is the most prevalent drug-related cause of acute liver failure, with hepatic injury occurring as a consequence of the drug's metabolism properties.[24]"
https://www.ncbi.nlm.nih.gov/books/NBK482369/
Since a Harvard study consigned by HHS showed that less than 1% of vaccine adverse events are reported, how many acetaminophen deaths and adverse events can we suppose may go unreported, let alone liver damage?

[edit add 12-7-23] "DARPA Recommended Ivermectin ["As a Curative"] In the Event of a Coronavirus Pandemic".
https://rumble.com/v2ed7lm-darpa-recommended-ivermectin-as-a-curative-in-the-event-of-a-coronavirus-pa.html
Transcript of video: "North American science spent 15 years figuring out what to do with the next COVID. It was back 2002-2003 the original SARS-CoV-1 occurred and so all sorts of experiments went on to determine what would be a useful response were something similar to occur. And the research was done. The research was all done by 2015 and 2016. And DARPA, the American research arm of the U.S. military, specifically knew and specifically recommended and passed the information on to the CDC, that ivermectin in particular was the absolute #1 product to be used in the event of a corona virus pandemic. It was fully known that ivermectin and certainly hydroxychloroquine as well, were highly anti-viral and immune modulatory and those two things were the key to modulate the immune response plus being anti-viral as well, those elements were both totally proven invitro and invivo with animals so that it was known, and of course we know it is completely safe for humans because these medications have been used for 35-40 years in humans, so that's what was sitting there ready to be used at the next pandemic."
https://rumble.com/v2ed7lm-darpa-recommended-ivermectin-as-a-curative-in-the-event-of-a-coronavirus-pa.html [end edit]


[edit add 10-3-23] Big Pharma's captured government agencies had to go against ivermectin full force, because if it's efficacy for treatment had been admitted to, it would have been unlawful for the government to issue emergency use authorization for Remdesivir, let alone the experimental, genetically engineered, chemically enhanced, innate immune response reprogramming, leaky, escape mutant training COVID "vaccine":
https://twitter.com/i/status/1708595061540491447 or:
https://rumble.com/v2wuv4b-rfk-jr-why-they-didnt-want-ivermectin-to-be-effective-against-covid-joe-rog.html [end edit]

[edit add from another thread] Even effective in later treatment as IVM is also anti-inflammatory:  "The blood oxygen level of the first patient treated in early April was 70%, and dropped to just 50% within hours. After receiving the invermectin, the patient stabilized within 24 hours and was discharged from the hospital in one week."
https://www.covid-19forum.org/index.php?topic=461.msg738#msg738

Part of the value of this video is to help in understanding that our care is up to us and that our doctor may benefit from our input to help in determining a course of treatment that is best for us. Indeed a doctor may be reluctant to prescribe medication off-label, and might not even discuss the possibility, unless the patient brings it up. Doctors often don't have the time that you may have to investigate the latest information. (scroll to 6:00 mark and again at 17:15)
https://trialsitenews.com/dr-jean-jacque-rajter-and-dr-juliana-cepelowicz-rajter-discuss-ivermectin-in-broward-county-podcast-s2-e-27/

https://youtu.be/nzqnAIfEbv4

 [end edit]
______________________________________

230 million people in the Indian state of Uttar Pradesh, 310,783 COVID cases in April, cut 97.1% in June, and just 22 cases by August
https://www.covid-19forum.org/index.php?topic=1068.0


Ivermectin has demonstrated efficacy for many other viruses as well (post further down):
https://www.covid-19forum.org/index.php?topic=461.msg1551#msg1551

[edit 2-22-21] The miracle drug ivermectin has even shown usefulness in cancer treatment! (post further down):
https://www.covid-19forum.org/index.php?topic=461.msg2545#msg2545
Anti-cancer effects in 9 more studies at this link:
https://www.covid-19forum.org/index.php?topic=461.msg3705#msg3705 [end edit]


[edit add 12-3-21] "Zendaya’s Parents Stopped Telling Her What To Wear When She Was 2
UPDATE: COVID-19 Cases Plummeted in Indonesia After Government Authorized IVERMECTIN For Treatment – Big Pharma Vaccines Made Little Difference"
https://www.thegatewaypundit.com/2021/10/update-covid-19-cases-plummeted-indonesia-government-authorized-ivermectin-treatment-big-pharma-vaccines-made-little-difference/ [end edit]

[edit add 10-27-21] Cost of ivermectin is about $168/kg, or a box of 100 12mg pills sells for as low as $2.19 (41:15 mark in this video: youtube.com/watch?v=vYF8bnmdQfY) [end edit]

[Edit add 10-14-21] Ivermectin has 22 different mechanisms of action against the SARS CoV2 virus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203399/
Compared to Big Pharma's FDA's disingenuous and misleading piece on it at the following link in this thread:
https://www.covid-19forum.org/index.php?topic=461.msg2162#msg2162 [end edit]

[Edit add 8-8-21] On the delta varianthttps://covid19criticalcare.com/
Uncensored FLCCC videos that escaped YouTube's evil censorship: https://odysee.com/$/search?q=flccc



Edit add on 1-20: While humane, competent clinicians that care about their COVID patients have been successfully treating them with off-label use of ivermectin (and hydroxychloroquine) ever since April of 2020 (since March in the case of HCQ), as of January 14th 2021 the NIH finally eased restrictions on Ivermectin from being recommended solely for participants in drug trials, to expressing no recommendation either for or against ivermectin. In large part thanks to board certified critical care and ICU pulmonary care specialist Dr. Pierre Kory's passionate and irrefutable congressional testimony. This gives ivermectin the same recommendation status as widely used but comparatively worthless convalescent plasma as well as monoclonal antibodies.

[edit add 6-28-21] The epitome of Big Pharma's shill's unbridled evil:

"Ivermectin Wins in Court Again: For Human Rights
By Justus R. Hope, MD Apr 19, 2021 Updated Apr 21, 2021

One dose of Ivermectin was all it took to get 81-year-old John Swanson off the ventilator. John’s wife Sandra could not believe it. His story is remarkably similar to other cases of patients who were on their way out with advanced COVID-19 but saved when Ivermectin was added.

Ralph Lorigo is the lawyer who now has won three court orders forcing New York hospitals to administer Ivermectin to dying patients. Incredibly, these three hospitals and their lawyers fought against the patients, arguing they did not have the right to receive the drug despite a valid prescription written by their doctors. In essence, the argument was that they did not have the right to try a potentially life-saving medication."
more
https://www.thedesertreview.com/opinion/letters_to_editor/ivermectin-wins-in-court-again-for-human-rights/article_98d26958-a13a-11eb-a698-37c06f632875.html [end edit]

If you had any doubts as to the evil and corruption within the revolving door or Big Pharma/government bureaucracy, check the outrage in this post in this forum thread.

FLCCC Alliance Response to the NIH Guideline Committee Recommendation on Ivermectin use in COVID-19
dated January 14th, 2021:
"However, the FLCCC considers the Panel’s unwillingness to provide more specific guidance in support of the use of ivermectin in COVID-19 to be severely out of alignment with the known clinical, epidemiological, and observational data. Our detailed response to the Panel’s criticism of the existing evidence base is below."
https://covid19criticalcare.com/wp-content/uploads/2021/01/FLCCC-Alliance-Response-to-the-NIH-Guideline-Committee-Recommendation-on-Ivermectin-use-in-COVID19-2021-01-18.pdf

Dr. Pierre Kory:  "If you are taking Ivermectin you will not contract COVID-19. I repeat, if you are taking Ivermectin you will not contract COVID-19."

[edit add 7-23-21] As we can witness in the player below, Google/YouTube even banned congressional testimony by a board certified intensive care unit pulmonologist when it didn't fit Anthony Fauci's NIH's death sentence for so many to, "go home and isolate" with the absence of recommendation for early treatment of COVID-19.
Anybody that depends on Google/YouTube for information cannot have any interest in truth. (Anti)social and legacy media lies and Big Tech censorship have resulted in the completely unnecessary deaths of well over a half a million Americans and millions more around the world. This is their legacy: https://c19legacy.com/

Fortunately the video can still be accessed at BitChute on this link:
https://www.bitchute.com/video/NSil15MibqlM/
[end edit]

https://www.youtube.com/watch?v=28YV8TfTieE

[added 6-12-21] Dr. Pierre Kory on the DarkHorse Podcast With Bret Weinstein on COVID Ivermectin Public Health Crimes
https://www.bitchute.com/video/a3a0EOIe8aK1/
[end edit]


Studies

Frontline Covid-19 Critical Care Alliance - A group of 10 doctors/specialists and scientists that have logged nearly 2,000 peer reviewed scientific papers between them.
https://covid19criticalcare.com/


https://youtu.be/Gq0Js3S-YGU

We have to get serious NOW! As things may get a lot worse this winter.
Long term side effects from allowing the disease to linger could impact the victim for life. EARLY treatment is key!

https://www.youtube.com/watch?v=xy8XcBodQv0

If the U.S. had a national policy of treating COVID immediately upon the presentation of symptoms with Ivermectin (per I-MASK+ protocol (specifics at this link)), except perhaps pregnant or lactating women (who could use the hydroxychloroquine Zelenko Protocol instead), the "pandemic" would be over. Life could go on normally with rapid herd immunity. Simply look at the many examples in this post, including the 8 Peruvian states in the following chart, that clearly demonstrate this. And blessedly the cost of Ivermectin is about $5 to $10 per dose.

More on specifics of the I-MASK+ prophylaxis and treatment protocols in our prevention category at this link:
https://www.covid-19forum.org/index.php?topic=535.0

"Real-World Evidence: The Case of Peru. Causality between Ivermectin and COVID-19 Infection Fatality Rate"
https://www.researchgate.net/publication/344469305_Real-World_Evidence_The_Case_of_Peru_Causality_between_Ivermectin_and_COVID-19_Infection_Fatality_Rate

"Conclusion
In these eight Peruvian State analyses, Ivermectin distributions preceded sound reductions in excess deaths and case fatality rate (CFR). The variation in the number of detected cases nor the vulnerable population decrease can explain this reduction. Other possible explanations, such as cross-immunity with dengue, or mere causality, have been discarded due to their lack of consistency in this study.
Treatment with ivermectin is the most reasonable explanation for the decrease in number of deaths and fatality rate in Peru. Its implementation in public policies is a highly effective measure to reduce the excess deaths and IFR  of COVID-19."



Take Iquitos (Peru) for example with their pre-hospital "Health center closed due to decrease in cases of COVID-19 in Iquitos."
https://juanjchamie.medium.com/what-happened-in-iquitos-peru-3a2828ae3bcf



"COVID-19 Mexico Ignoring the national guidelines, the Mexican State of Chiapas has decided to treat early with teams going door to door and giving a cocktail of drugs with ivermectin since July."
Check results at this link:
https://twitter.com/jjchamie/status/1334985329913245696/photo/1

Ivermectin even demonstrates efficacy in later stages of COVID-19 disease.

Dr. Jean-Jacques Rajter and Dr. Juliana Cepelowicz Rajter Discuss Ivermectin In Broward County Florida
https://trialsitenews.com/dr-jean-jacque-rajter-and-dr-juliana-cepelowicz-rajter-discuss-ivermectin-in-broward-county-podcast-s2-e-27/

"“There’s a common denominator here,” said Hibberd. “This drug is salvaging people from their death bed.”
In some cases, doctors reported just one dose of ivermectin markedly improved a patient’s condition. U. S. patients received a single oral dose, and some of them received a booster dose seven days later. The FDA-approved dose for parasitic infections was used."
"The blood oxygen level of the first patient treated in early April was 70%, and dropped to just 50% within hours. After receiving the invermectin, the patient stabilized within 24 hours and was discharged from the hospital in one week."
https://www.covid-19forum.org/index.php?topic=461.msg738#msg738

Prevention and cure - "Ivermectin, A cure for Covid VERY SAFE, VERY CHEAP"
https://www.bitchute.com/video/RVyQuKDWGiSg/

Review contraindications with your doctor before beginning treatment with Ivermectin or any other therapeutic.

DO NOT start corticosteroids too early as they "....decrease your immune response and allow for increased viral replication....." - Dr. Paul Marik at the 31:40 minute mark in second video above.

"Who should not take Ivermectin?
The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:"
https://www.webmd.com/drugs/2/drug-1122/ivermectin-oral/details/list-contraindications

Check drugs.com for dosage or visit the Ivermectin protocol page here: https://www.covid-19forum.org/index.php?topic=535.0

"Group of doctors highlight results of successes in more than 6,000 patients with Covid-19 treated with the drug ivermectin."
"The advantage of Ivermectin, Redondo points out, is that it is a well-known and studied drug because it has been used for more than 30 years in humans and for around 45 years in animals....."
https://www.covid-19forum.org/index.php?topic=461.msg650#msg650

EVMS CRITICAL CARE  COVID-19 MANAGEMENT PROTOCOL
https://www.evms.edu/media/evms_public/departments/internal_medicine/EVMS_Critical_Care_COVID-19_Protocol.pdf

Ivermectin (anti-parasite medication) has been around 50 years and COVID-19 results look very positive for this also inexpensive ($20) protocol. Indeed far superior to expensive, less effective, drugs like Remdesivir.
https://www.goodrx.com/ivermectin

Ivermectin at drugs.com
"Ivermectin tablets (Stromectol) is an approved medicine by the FDA for use in intestinal worms"
https://www.drugs.com/ivermectin.html
https://www.drugs.com/medical-answers/ivermectin-treat-covid-19-coronavirus-3535912/
____________________________________________

"Ivermectin treatment is a ‘real killer of coronavirus’: Professor Thomas Borody
5,000 fold reduction in volume of virus within 48 hours
" (in vitro)

For Ivermectin studies go to the early and late study categories in this forum.

https://www.youtube.com/watch?v=F6A6RFDprIs
__________________________________

Top Israeli Scientist & Physician Embraces Ivermectin for Clinical Trial & Raises Possibility the Drug Could Beat COVID-19
https://trialsitenews.com/top-israeli-scientist-physician-embraces-ivermectin-for-clinical-trial-raises-possibility-the-drug-could-beat-covid-19/
___________________________________________

The FDA has warned against self-medicating with Ivermectin, and particularly the product intended for veterinary purposes.
https://www.fda.gov/animal-veterinary/product-safety-information/fda-letter-stakeholders-do-not-use-ivermectin-intended-animals-treatment-covid-19-humans

Developing countries are certainly beating the pants off of developed countries in terms of lower death rates!
Paraguay
https://public.tableau.com/profile/jchamie#!/vizhome/COVID-19PARAGUAY/Paraguay
survey sent to doctors around the world - what works best?
https://public.tableau.com/profile/jchamie#!/vizhome/WhatisthebestmedicinetofightCOVID-19/DRUGS
The drug Ivermectin has been approved by Belize’s Ministry of Health
https://lovefm.com/ministry-of-health-and-wellness-approves-ivermectin-as-a-covid-19-treatment/

[edit 6-17-22] (almost none of the studies listed included all important zinc (let alone doxycycline or azithromycin to complete the triple therapy), so could not be expected to have the most favorable results, yet in spite of these handicaps ivermectin still put in a good showing)
Comparing studies VS 99+% success rates in evidenced-based medical practice

https://c19ivermectin.com/


[end edit]

"Ivermectin Side Effects on Humans: Scientists Debate Coronavirus Cure"
https://heavy.com/news/2020/04/ivermectin-side-effects-coronavirus-cure/

https://youtu.be/Xl9t2YrHw7Y

What seems to be the bigger advantage of Ivermectin protocols (Ivermectin+zinc+doxycycline for example) over HCQ protocols is that they appear to work over a little longer/later period during the early outpatient setting, and also take just one dose, perhaps with a followup dose or two depending on the viral load. Even once every couple of weeks or month as prophylaxis, but with seemingly quicker response as prophylaxis, than the 4-6 weeks of weekly dosing that HCQ takes. Also shows efficacy in the later hospital inpatient setting.
Also seems to have more anti-inflammatory advantages for later COVID stages.

"The study team found that the already approved and widely used antiparasitic drug was even more effective for those patients experiencing severe pulmonary challenges."
https://trialsitenews.com/icon-study-evidencing-efficacy-of-ivermectin-against-covid-19-published-in-peer-review-journal-chest/

When YouTube bans the video at the link below you can access it at this BitChute video that also has the unrelated second half edited out:
https://www.bitchute.com/video/i3rlgX5MtyfK/

https://www.youtube.com/watch?v=oA-fTaGadyc

The WHO regarding safety "Mass treatment with ivermectin: an underutilized public health strategy"
https://www.who.int/bulletin/volumes/82/8/editorial30804html/en/
While that is a reference to treating en masse for parasites, the Peruvian individual States models illustrated above employed mass distribution of Ivermectin for COVID-19.

Scroll to 3:20 minute mark to skip general world stats on coronavirus to the beginning of the discussion on the mechanism of action of Ivermectin.

https://www.youtube.com/watch?v=qc6VV7ue4cE

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
https://pubmed.ncbi.nlm.nih.gov/32251768/

https://www.youtube.com/watch?v=cANzneWatIc

https://youtu.be/mKLGXebK-C0

An interesting paper on the history of human use of ivermectin:
"Ivermectin, ‘Wonder drug’ from Japan: the human use perspective"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043740/

https://youtu.be/DCpiHHG0R2k
« Last Edit: February 18, 2024, 10:45:21 AM by admin »
Over a million Americans have died completely unnecessary, horrific, deaths from COVID-19. Do you have a plan in place to help your family dodge the average $73,300 COVID hospital bill, through prevention and a $20 EARLY treatment protocol? https://www.covidtreatmentoptions.com/

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Re: Ivermectin treatment is a ‘real killer of coronavirus’: Professor
« Reply #1 on: November 22, 2020, 11:01:35 AM »
Edit add:  And the mass murder by Google/YouTube continues as evidenced in the censorship of videos below by highly successful COVID-treating physicians. Anyone who uses Google for anything should be ashamed of themselves for supporting Google's genocide of blacks, Hispanics, elderly, sick, poor and least able among us, through censorship of truth.

https://www.youtube.com/watch?v=IyXsAK980vU

This is the prior censored upload of this video by Chris Martenson of Peak Prosperity.

https://youtu.be/CuHq12B_Tvk

Following video links from this blog:  https://www.reddit.com/r/ivermectin/comments/gtt5vq/gold_standard_ivermectin_protocol_blog_by_adam/

https://youtu.be/kE2EcKm5Uj4

Dr Jean Jacques Rajter and his wife Dr. Juliana Cepelowicz Rajter are amazing and dedicated clinicians who back in April of 2020 were early pioneers in the repurposing of Ivermectin for the highly effective treatment of COVID-19.
This is a link to their medical practice:
https://www.healthgrades.com/physician/dr-jean-jacques-rajter-379sc

Part of the value of this video is to help in understanding that our care is up to us, and our doctor may need our help in determining a course of treatment. (scroll to 6:00 mark and again at 17:15)
https://trialsitenews.com/dr-jean-jacque-rajter-and-dr-juliana-cepelowicz-rajter-discuss-ivermectin-in-broward-county-podcast-s2-e-27/

https://www.youtube.com/watch?v=nzqnAIfEbv4

"Ivermectin is to virus as penicillin is to bacteria."
"If everyone in the world took this drug once a week this entire pandemic would be over in a couple of weeks. Tops. We could put a full stop on this pandemic tomorrow."
WHO regarding use for parisites: "Mass treatment with Ivermectin is an underutilized public health strategy."

https://youtu.be/RDzBdDhyJzI

3.7 billion doses have been prescribed over the last 30 years

https://youtu.be/BLWQtT7dHGE

Abject moron Senator Gary Peters moronic outburst. So who can we guess is his puppeteer? Hint, Bill Gates - perhaps the most evil global puppeteer of all time? Pissed that such cheap simple time tested replacements are vying to eliminate a need for his risky rushed vaccine.

https://youtu.be/nxw1voRlS1g
« Last Edit: February 22, 2021, 07:02:49 AM by admin »
Over a million Americans have died completely unnecessary, horrific, deaths from COVID-19. Do you have a plan in place to help your family dodge the average $73,300 COVID hospital bill, through prevention and a $20 EARLY treatment protocol? https://www.covidtreatmentoptions.com/

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Re: Ivermectin treatment is a ‘real killer of coronavirus’: Professor
« Reply #2 on: November 22, 2020, 11:02:59 AM »
[moved to the top of this post on 3-17-21]
https://www.hpj.com/ag_news/could-ivermectin-be-an-answer-to-both-parasites-and-pandemics/article_0b578c96-5529-11eb-b6bc-f78e273cbf37.html

"Could Ivermectin be an answer to both parasites and pandemics?
    By Lacey Newlin Jan 12, 2021 Updated Jan 14, 2021

Note

Ivermectin should only be taken under the care and supervision of a physician.

It is sitting on most veterinary supply shelves and a staple for numerous cattle owners, but the drug Ivermectin could also be a viable preventative and treatment for critically ill COVID-19 patients. Ivermectin, a Food and Drug Administration-approved antiparasitic drug, is most commonly recognized in the agricultural community for its use in the treatment of parasites in livestock.

However, it is also used to treat several tropical diseases in humans, including onchocerciasis, helminthiases and scabies.

In March 2020 several Australian scientists published an in vitro medical paper showing that Ivermectin inhibited replication of SARS-CoV-2, also known as the coronavirus. (Photo by Emin Baycan on Unsplash.)

Ivermectin can also treat some parasitic worms and external parasites, such as head lice, and skin conditions such as rosacea. So how did some researchers make the connection between a drug often used in cattle and the treatment of COVID-19?

According to Paul Marik, M.D., in March 2020 several Australian scientists published an in vitro medical paper showing that Ivermectin inhibited replication of SARS-CoV-2, also known as the coronavirus.

“Now this was an in vitro test tube study, not a clinical study, so it was widely distributed and got people’s attention, but at that time there was no clinical data,” he said.

Dr. Marik, a professor of medicine and chief of pulmonary and critical care medicine at Eastern Virginia Medical School in Norfolk, Virginia, and a founding member of the Front Line COVID-19 Critical Care Alliance, said researchers have previously shown that Ivermectin was effective for a whole host of other viruses including West Nile, Zika and HIV. Apart from being an effective anti-parasitic drug, it also has broad-spectrum anti-viral and anti-inflammatory properties.

“All of these properties make it the ideal drug to use for the coronavirus,” Marik said.

The National Institute of Health states that Ivermectin impedes the host importin alpha/beta-1 nuclear transport proteins, which are a central part of the intracellular transport process that viruses seize to increase infection by pacifying the host’s antiviral response. The NIH refers to the drug as a host-directed agent, which is why it has been so successful with broad-spectrum activity in vitro against the viruses.

However, the NIH states that studies have shown reaching the plasma concentrations required for achieving antiviral effectiveness would involve quantities up to 100 times the FDA-approved dosage for humans, which has not been studied enough to know the possible ramifications for patients. At this time, the NIH COVID-19 treatment guidelines do not recommend the use of Ivermectin for the treatment of COVID-19, except in a clinical trial. Marik, one of the most published critical care doctors in the world, is adamant that the NIH’s recommendation is incorrect.

“Currently to date, there are 18 randomized control trials that have been published, which show Ivermectin decreases time of virus shedding, length of hospital stays and mortality,” he said. “The mortality of the Ivermectin groups in these studies was 2.3% and in the control group is was 10%. There is absolutely no doubt, this drug decreases viral replication, improves symptom resolution and mortality.”
hal-gatewood-nhG5gix93es-unsplash.jpg

At this time, the National Institute of Health’s COVID-19 treatment guidelines do not recommend the use of Ivermectin for the treatment of COVID-19, except in a clinical trial.

[Two days after this article was published the NIH changed the guidelines to recommending neither for or against, giving ivermectin the same status as widely used (but not proven to be effective) convalescent plasma therapy and monoclonal antibodies.]

Further supporting his claims, Marik said one of his colleagues in Houston, Texas, has been prescribing Ivermectin since March 2020 when the initial studies came out and his hospital has the lowest mortality of any hospital in the entire world.

The data does not lie

In December 2020, Pierre Kory, M.D., associate professor of medicine at St. Luke’s Aurora Medical Center in Milwaukee, Wisconsin, and founding member of the FLCCC Alliance, testified in front of the Senate Homeland Security and Governmental Affairs Committee hearing on the effectiveness of Ivermectin as both a prophylaxis and a treatment for COVID-19 patients.

Dr. Kory referenced a study conducted in Argentina, in which 800 health care workers were given Ivermectin as a preventative medication and none of them were infected by the coronavirus during the experiment. Kory continued by saying among the 400 health care workers that were not prophylaxed with Ivermectin, 237 individuals or 58% of the group contracted the virus.

“If you take it, you will not get sick,” Kory said. “It has immense and potent anti-viral activity.”

Kory said four large, randomized controlled trials with over 1,500 patients are in progress and information is being gathered on Ivermectin as a prophylaxis and the evidence collected so far has overwhelmingly shown it is immensely effective. He went on to say there are three randomized control outpatient trials underway that have shown while taking Ivermectin, the need for hospitalization or death decreases. To further bolster its claims, the FLCCC Alliance indicated a meta-analysis of the data compiled from their studies was recently completed by an independent research group and it determined the chances Ivermectin is ineffective in treating COVID-19 are 1 in 67 million.

“The most profound evidence we have is in the hospitalized patients,” Kory said. “We have four randomized control trials there, all showing the same thing: you will not die or you will die at much, much lower rates. These are statistically significant, large magnitude results if you take Ivermectin. It is proving to be a wonder drug and it is critical for its use in this disease.”

In addition, Marik said studies of pre- and post-exposure prophylaxis, show a dramatic effect in reducing the risk of infection when exposed.

“If one person in your household contracts the virus you have about a 50% chance of getting COVID-19,” Marik explained. “Based on the randomized trails, if you take Ivermectin, you can reduce the risk from about 50% to about 6%.”

Marik and Kory both emphasized the need for prevention of COVID-19, rather than treatment.

“I’m a lung and ICU specialist and I have cared for more dying COVID patients than anyone can imagine,” Kory said. “They’re dying because they can’t breathe and by the time they get to me in the ICU, they’re already dying and almost impossible to recover.

Marik said if the health care system were to focus on prevention and early treatment with Ivermectin, hospitals would empty, the risk of dying would decrease and that would allow the economy to open.

“Any further deaths are going to be needless deaths and I cannot be traumatized by that,” Kory said. “I cannot keep caring for patients when I know they could have been saved with earlier treatment and the drug that will treat them and prevent hospitalization is Ivermectin.”

Have we been handling the virus correctly?

Apart from the NIH not endorsing Ivermectin, one of the faults Marik finds with the NIH’s guidelines is that it does not recommend any early treatments for patients with coronavirus.

“I get hundreds of emails and the typical message goes ‘I have COVID, I contacted my doctor. My doctor said there is nothing I can do. I must stay at home until I turn blue and can’t breathe and then to the emergency room,’” Marik explained. “That is the current recommendation of the NIH. The only treatment they recommend is Remdesivir, which has been removed by the World Health Organization because it has been deemed ineffective. The solidarity trials of Remdesivir showed no benefit, yet it is the most commonly prescribed medication in this country.”

[NIH guidelines have resulted in this genocide of hundreds of thousands of Blacks, Hispanics, elderly, sick and poor - around the world - and those responsible need to be held accountable and prosecuted for crimes against humanity.]

Additionally, Marik said convalescent plasma, a commonly prescribed therapy, should not be used at all in COVID-19 patients.

“We absolutely and categorically know convalescent plasma does not work,” Marik said. “It’s an outrage that doctors are prescribing medications that do not work. In the whole history of medicine, there is only one study that actually shows the benefit of convalescent serum and that was for the treatment of Argentine hemorrhagic fever, published in 1979. Anyone with any understanding of COVID-19, would know this is not a blood-borne disease and convalescent plasma is not going to work and actually exposes the patient to enormous risks.”

Marik cites a misunderstanding of the virus and the influence of the pharmaceutical industry for why these treatments have been used, while Ivermectin has been ignored. According to Marik, the Centers for Disease Control and Prevention’s website lists Ivermectin as a dangerous drug and that it causes hepatitis, drug reactions, comas and seizures. He said 3.7 billion people have used it (since its use began in the 1970s) and in all those people there was only one case of hepatitis in one patient and he said the association with hepatitis and Ivermectin was very loose.

“It is on the WHO’s list of essential medications and is probably one of the safest medications known to mankind,” Marik continued. “The safety issue is nothing more than lies and propaganda and people just need to look at the literature to validate that claim. What is happening is a moral outrage and there are a lot of people who are going to have to be held accountable for all these avoidable deaths. This is a cheap, effective drug that is readily available and people are not going to profit from it—it’s quite simple. I don’t think there is another explanation.”

Marik said he and his colleagues at the FLCCC Alliance have had a target on their backs since going public on social media with the studies they have conducted with Ivermectin.

“Our information has been taken down from YouTube and Facebook because these sites are claiming we are promoting medical misinformation,” Marik explained. “The absurdity in that is quite striking because we haven’t uttered a single word that is not true. It’s all based on science and truth and yet we are being censored.”

[This censorship has supported the genocide of hundreds of thousands of Blacks, Hispanics, elderly, sick and poor, and those responsible need to be held accountable and prosecuted for crimes against humanity.]

Marik said none of the physicians and scientists at the FLCCC Alliance have any vested interest or benefit from spreading the word about Ivermectin’s success with fighting COVID-19—they only want to save lives. Although Marik is relieved a vaccine has been developed, he still sees a great need for the use of Ivermectin.

“I’m not an anti-vaccination person, but we have 4,000 people dying every day,” he said. “I think the vaccine has a role, but whether it is going to be enduring we don’t know. Vaccinations are not going to stop the deaths right now, but Ivermectin in our protocol could stop them. It is going to take a long time for 60% to 70% of the entire world’s population to be vaccinated and we achieve herd immunity. We need to do something in the meantime.”

While Marik has received his first round of the vaccine, he plans to continue his 15 milligrams of Ivermectin every two weeks as a prophylaxis until he is fully protected by the vaccine. Recently the WHO assigned a group of doctors with the task of looking at the Ivermectin studies that have been conducted and they will present their takeaways from the findings soon, which could be a turning point in the use of the medication.

“I don’t know what they will decide to do, but we just hope they have the common sense and humanity to change their guidelines,” Marik said.

Lacey Newlin can be reached at 620-227-1871 or lnewlin@hpj.com.
_________________________________________________

https://dominicantoday.com/dr/covid-19/2020/09/29/doctors-cure-6000-patients-with-covid-19-with-ivermectin/
COVID-19 September 29, 2020 | 2:07 pm

Group of doctors highlight results of successes in more than 6,000 patients with Covid-19 treated with the drug ivermectin.

Santo Domingo, DR

At least 6,000 Covid-19 positive patients have been treated with excellent results using the drug ivermectin, by doctors belonging to the Rescue group, with health facilities located in Puerto Plata, La Romana, and Punta Cana.

The antiparasitic and antiviral drug, known in the market for 50 years, has been used by doctors in the country since the beginning of the epidemic to treat patients with the SARS-CoV-2 virus that causes the Covid-19 disease; when the first cases began to appear and in the absence of a specific treatment.

The details were offered by Dr. José Natalio Redondo, president of the Rescue Group when he participated as a guest in “La Cita con el Covid,” which broadcasts every Monday at 9:00 pm Listindiario.com.

The advantage of Ivermectin, Redondo points out, is that it is a well-known and studied drug because it has been used for more than 30 years in humans and for around 45 years in animals, while around the world a trillion doses are given per year no side effects.

He said that the group had registered about 6,000 patients with outpatient emergency and consultation services with promising results, “and it forces us to follow the same policy of treatment and management scheme.” Redondo, who, along with a group of researchers from the Rescue Group, has been a promoter of this treatment. He said that although there are still many things that are unknown about this disease, it is undoubted that progress has been made to the point that medicines and drugs are already available, recognized, and approved procedures for the different phases of the disease.

The dose

He stressed that several studies reliably demonstrate the antiviral effect on the symptoms of the patient that has Ivermectin and that in laboratory tests, a significantly rapid reduction in viral load is noted when it is used in the early phase.

He explained that the current dose is that a person between 80 and 90 kilos should take six or seven tablets [please note it comes in many sizes including 3mg pills] in total, administered all together or in daily doses, preferably in the early stage of symptoms. “Our group is giving it all six meetings in the emergency to Covid patients,” he said.

We have computed more than 4,500 patients treated in the emergency with extraordinary results that are measured concerning the duration of the disease whose results are going to be published internationally,” he said. However, he recognizes that the panacea against the disease will be the vaccine.

He favored the country to continue releasing more restrictive measures, especially in places where there is less incidence of the virus that produces Covid-19.

The medicine specialist pointed out that health centers are currently receiving more patients decompensated by chronic diseases than Covid.

He said that patients with diabetes, heart, kidneys, and cancer, among other chronic diseases, were neglected and had not been attending their check-ups due to fear of the Covid.

He specified that health facilities are currently receiving patients of this type in delicate conditions, including more strokes and heart attacks.

Aftermath for years

He considered that health systems should continue to be strengthened because there is no doubt that the consequences of the disease in individual patients will last for months or years.

“There is no doubt that it is a disease that is shaking the foundations of science. I am convinced that the person who gets severe pneumonia from Covid will take two years to recover, even if he returns to his everyday life, the person with circulatory disease can take much longer to return to the previous recovery,” he declared.

Low incidence of Covid

Redondo said that currently, the incidence of the Covid virus had dropped considerably in the country.

For example, he cited that in the Bávaro Punta Cana area, it is only 10% compared to previous months, in La Romana Bayahíbe, it has dropped to 25 to 30% and in Puerto Plata to 50%.

He estimated that if it is possible to maintain this natural environment and specific interventions that have been made, it is in conditions without a doubt to receive tourists without any inconvenience.

He said that with the Covid, it is advisable to test the effect, that is, to continue opening the economy little by little, but observing and monitoring to re-restrict in case of an increase in cases, in addition to continuing to educate the population because much depends on citizen responsibility.

At least 6,000 patients positive for Covid -19 have been treated with the drug ivermectin by doctors belonging to the Rescue group, with health facilities located in Puerto Plata, La Romana, and Punta Cana, with excellent results.

José Natalio Redondo, president of Grupo Rescue, and journalist Doris Pantaleón.
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Re: Ivermectin treatment is a ‘real killer of coronavirus’: Professor
« Reply #3 on: November 22, 2020, 11:07:06 AM »
https://www.trialsitenews.com/ivermectin-study-reveals-fantastic-results-100-of-60-patients-better-in-an-average-of-just-under-6-days/

Ivermectin Study Reveals Fantastic Results: 100% of 60 Patients Better in an Average of Just Under 6 Days

Jun 28, 2020

excerpt:

"The Results

Much like the results from Dr. Rajter at Broward County, Florida, United States and Dr. Tarek Alam, Bangladesh Medical College, the results here were quite positive.

Group A, the Ivermectin group, experienced a 100% recovery rate, with a mean symptomatic recovery duration of 5.93 days and negative PCR was on 8.93 days. The Group B results (Hydroxychloroquine and Azithromycin) was 96.36%, 6.99 days and 9.33 days respectively.

55.10% of the patients in Group A (Ivermectin) gained symptomatic recovery on the 5th day. A mild degree of adverse effect was noted by 31.67% of patients; lethargy in 14 (23.3%), nausea in 11 (18.3%) and occasional vertigo in 7 (11.66%) of patients.

In the meantime, Group B experienced some degree of adverse effects; 13 (23.21%) mild type of blurring of vision and headache; 22 (39.2%) increased lethargy and dizziness, 10 (17.85%) occasional palpitation, and 9 (16.07%) experienced nausea and vomiting.

Conclusion

The Upazila Health & Family Planning Officer’s (UHFPO) Office, Chakoria, Cox’s Bazar in collaboration with Abu Taiub Mohammad Mohiuddin Chowdhury, First Affiliated Hospital Xi’an Jiaotong University in China has come to the conclusion that in regards to treatment outcome, adverse effect and safety, the Ivermectin and Doxycycline combination is superior to Hydroxychloroquine-Azithromycin therapy in the case of mild to moderate degree of COVID-19 patients. The Bangladeshi and Chinese team found that both treatments were effective in this study. However, the Ivermectin results were superior to Hydroxychloroquine."
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Re: Ivermectin treatment is a ‘real killer of coronavirus’: Professor
« Reply #4 on: November 22, 2020, 11:28:10 AM »
Another $20 time tested 50-year old drug is found to be superior to any of the crap new patented meds to come out like remdesivir.
Isn't it well past time to select influential persons at NIH, FDA, CDC and particularly Big Pharma to prosecute for crimes against humanity and genocide of elderly, sick, poor and minority Americans, to inspire some insiders to start singing for immunity?
Since these are crimes against all of humanity on a global scale is it time to get Interpol involved?
__________________________________

Ivermectin from our friends at c19. Looks like very positive results with this also inexpensive ($20) medication:
https://www.goodrx.com/ivermectin

Click on the studies and follow links to "Source" to see the published study pages

https://c19ivermectin.com/    (all)

https://c19ivermectin.com/#early

https://c19ivermectin.com/#late

Examples:

EARLY

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3714649

https://www.medrxiv.org/content/10.1101/2020.10.31.20223883v1

https://www.medrxiv.org/content/10.1101/2020.09.10.20191619v1

https://c19ivermectin.com/chang.html

LATE

https://www.researchsquare.com/article/rs-109670/v1

https://www.researchsquare.com/article/rs-100956/v1

https://www.medrxiv.org/content/10.1101/2020.10.29.20222505v1

https://www.medrxiv.org/content/10.1101/2020.10.26.20219345v1

https://www.sciencedirect.com/science/article/pii/S030028962030288X

https://www.researchgate.net/publication/343305357_A_Case_Series_of_100_COVID-19_Positive_Patients_Treated_with_Combination_of_Ivermectin_and_Doxycycline

http://bcpsjournal.org/article_details.php?oid=762
_________________________________________________

promising website that I haven't explored
https://covid.us.org/ivermectin/
_________________________________________________

A lot of studies listed on this site
https://www.bloomberg.com/press-releases/2020-08-19/ivermectin-triple-therapy-protocol-for-covid-19-to-australian-gp

WHO:
Mass treatment with ivermectin: an underutilized public health strategy
https://www.who.int/bulletin/volumes/82/8/editorial30804html/en/
 
ResearchSquare:
A Randomized Trial of Ivermectin-Doxycycline and
Hydroxychloroquine-Azithromycin therapy on COVID19 patients
https://www.researchsquare.com/article/rs-38896/v1
 
MedRxiv:
Effectiveness of Ivermectin as add-on Therapy in COVID-19 Management (Pilot
Trial)
https://www.medrxiv.org/content/10.1101/2020.07.07.20145979v1
 
Journal of Antibiotics:
Ivermectin: a systematic review from antiviral effects to COVID-19
complementary regimen
https://www.nature.com/articles/s41429-020-0336-z
 
ResearchGate:
A Case Series of 100 COVID-19 Positive Patients Treated with Combination of
Ivermectin and Doxycycline
https://www.researchgate.net/publication/343305357
 
ermectin_and_Doxycycline
 
Journal of Bangladesh College of Physicians and Surgeons:
A Case Series of 100 COVID-19 Positive Patients Treated with Combination of
Ivermectin and Doxycycline
https://www.banglajol.info/index.php/JBCPS/article/view/47512
 
Journal of Bangladesh College of Physicians and Surgeons:
Comparison of Viral Clearance between Ivermectin with Doxycycline and
Hydroxychloroquine with Azithromycin in COVID-19 Patients
https://www.banglajol.info/index.php/JBCPS/article/view/47514
 
MedRxiv:
ICON (Ivermectin in COvid Nineteen) study: Use of Ivermectin is Associated
with Lower Mortality in Hospitalized Patients with COVID19
https://www.medrxiv.org/content/10.1101/2020.06.06.20124461v2
 
ChemRxiv:
Has Ivermectin Virus-Directed Effects against SARS-CoV-2? Rationalizing the
Action of a Potential Multitarget Antiviral Agent
https://chemrxiv.org/articles/preprint/12782258
 
on_of_a_Potential_Multitarget_Antiviral_Agent/12782258
 
Professor Borody says his research has led him to a triple therapy of
Ivermectin, zinc and an antibiotic - which are all TGA and FDA approved. The
therapy comprises:
 
1.  Ivermectin - TGA and FDA approved as an anti-parasitic therapy with an
established safety profile since the 1970s. Known as the "Wonder
Drug" from Japan.
2.  Zinc
3.  Doxycycline - TGA and FDA approved tetracycline antibiotic that fights
bacterial infections, eg. acne or urinary tract infections, viral and malarial
infections.
 
Professor Borody is involved in a Phase 2 study in the US to potentially
develop the triple therapy as a single "blister pack" compliance
product. He says, "Our study in the US is looking at developing the
triple therapy as a single product which requires FDA approval, even though
all 3 medications separately are already approved." [US clinical trial:
https://clinicaltrials.gov/ct2/show/NCT04482686?term=Ivermectin+borody]
 
About the Centre for Digestive Diseases (CDD)
 
The Sydney-based Centre for Digestive Diseases (CDD) provides patients with
innovative therapies not available in the rest of the world. The Hospital
features cutting-edge technologies enabling our specialists to provide
world-class treatments. Visit https://centrefordigestivediseases.com.
 
Professor Borody is best known internationally for his work in gut and its
mircobiome infections and re-purposing antimicrobial drugs for new diseases
including the triple therapy cure for peptic ulcers. His discoveries prevented
premature deaths in over 18,000 people and saved the Federal Government a
reported $10 billion. [THEMA Report]
 
Professor Borody developed a triple therapy for the treatment for Crohn's
Disease, and has developed 4 FDA approved pharmaceuticals for the USA and
international markets.
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https://www.newsmax.com/us/ivermectin-drug-virus/2020/05/22/id/968688/

"Breakthrough Drug: Ivermectin Shows 'Astounding' Results Against Coronavirus

By David A. Patten    |   Friday, 22 May 2020 11:16 PM

Reports Friday from multiple trials in the United States and abroad indicate a drug already approved by the FDA to treat parasitic infections is showing “astounding” results, and could represent a breakthrough in efforts to vanquishing the SARS-CoV-2 virus at the heart of the global pandemic.

Doctors have administered the drug ivermectin in several simultaneous trials in several countries sometimes in combination with other common medications.

Physicians who participated in the study report that patients’ viral loads began declining almost immediately after they began administering ivermectin, a widely available prescription drug approved to combat parasites, scabies and head lice.

It has not been approved for COVID-19 patients, but doctors familiar with clinical trials described patients’ results as dramatic.

Emergency medical physician Dr. Peter H. Hibberd, M.D., of Palm Beach County, Florida, told Newsmax Friday evening in an exclusive interview that he’s optimistic the drug will prove to be an important therapeutic advance, although he expects more trials will be needed before it wins FDA approval for use as a COVID-19 medication.

He noted it has impressed doctors in clinical trials on multiple continents.

“There’s a common denominator here,” said Hibberd. “This drug is salvaging people from their death bed.”

In some cases, doctors reported just one dose of ivermectin markedly improved a patient’s condition. U. S. patients received a single oral dose, and some of them received a booster dose seven days later. The FDA-approved dose for parasitic infections was used.

The drug first emerged as a possible coronavirus therapeutic after a study to be published in next month’s Antiviral Research journal by researchers in Victoria, Australia showed the drug wiped out the virus in a test tube.

On Thursday, a team of U.S. doctors led by Dr. Jean-Jacques Rajter at the Broward Health Medical Center in Fort Lauderdale, Florida, submitted findings to an institutional review board. According to a medical source familiar with the study, some 250 coronavirus patients were involved in the Broward trial. The results were dramatic, with “statistically significant improvement in mortality,” according to the source.

The blood oxygen level of the first patient treated in early April was 70%, and dropped to just 50% within hours. After receiving the invermectin, the patient stabilized within 24 hours and was discharged from the hospital in one week.   

It is important to note that while some patients are receiving the medicine on an emergency basis, the FDA on May 1 posted the following advisory: “While there are approved uses for ivermectin in people and animals, it is not approved for the prevention or treatment of COVID-19. You should not take any medicine to treat of prevent COVID-19 unless it has been prescribed to you by your health care provider and acquired from a legitimate source.”

In a separate trial on the other side of the globe, a team of doctors in Bangladesh reported Friday that they administered a combination of ivermectin and doxycycline, a common antibiotic, to 60 coronavirus patients there.

That team reported that within 72 hours after receiving the drug, their patients tested negative for the virus, and by the fourth day, they had recovered. Dr Tarek Alam, a senior doctor for the Bangladesh Medical College Hospital, told India’s ZeeNews that the results were “astounding” and said all patients “experienced full recoveries.

One reason the FDA is cautious is that the drug can interact with other medications, and in some cases can cause complications such as nausea, diarrhea, stomach pain, dizziness, a sudden drop in blood pressure, liver problems and other side effects.

The Gates Foundation is funding a third clinical trial of ivermectin in France, according to TrialSiteNews.com.

Hibberd said the ivermectin trials indicate it is an “effective therapy” that would provide a bridge to a vaccine and would potentially reduce the downside risk of catching the virus.

“It would mean we could go to work and not worry,” he said of the prospect of having an effective therapeutic medication. “You catch it, we treat you and we move on as a country.”

© 2020 Newsmax. All rights reserved.
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Clinically Approved Antiviral Drug in an Orally Administrable Nanoparticle for COVID-19
https://pubs.acs.org/doi/abs/10.1021/acsptsci.0c00179#

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Thank you for sharing this extremely important information for everyone to know. The problem is how are you going to get CDC, FDA, NIH, and NIAID to approve and recommend ivermectin for Covid-19 treatment. Without their approval, doctors are not allowed to prescribe ivermectin.
« Last Edit: December 20, 2020, 12:35:16 PM by Albert0365 »

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Thank you for sharing this extremely important information for everyone to know. The problem is how are you going to get CDC, FDA, NIH, and NIAID to approve and recommend ivermectin for Covid-19 treatment. Without their approval, doctors are not allowed to prescribe ivermectin.

Hi Albert, and welcome to the forum! Doctors in the U.S. are allowed to prescribe all approved medications for off-label use. That is, repurposed. Ivermectin is an approved drug. Off-label use is how so many highly successful treating physicians have been prescribing hydroxychloroquine ever since March.

Some cover their a$$ doctors are afraid to prescribe, outside the "standard of care", because they are more exposed to lawsuits in so doing. It isn't hard to understand since they have so much invested in getting licensed and thus so much to loose (their livelihood!). So patients take a back seat. I checked with my osteopathic doctor early on in the pandemic, to see if he would prescribe HCQ+AZ+zinc for myself and my very elderly mother, and he assured me that is what he had been prescribing for all his COVID patients. Ivermectin is pretty new to my radar screen so I will ask him about it this week.

Don't hold your breath waiting for those agencies to recommend or approve a generic $20 drug for COVID-19, since they are all owned by Big Pharma (along with politicians, TV networks, mass media, social media, hospitals, some doctors, etc. etc.) and none of the individuals or their agencies stand to have their palms greased by anyone that has anything to do with a cheap, 50-year old, off-patent, generic drug.  Also it seems to me that the efficacy of Ivermectin as prophylaxis as well as treatment, renders their vaccines irrelevant.

Consider the homicidal guidelines by NIH which would seem designed to put Americans into hospitals, in conjunction with Fauci's "go home and isolate" death sentence for elderly and high-risk individuals - which are the current "standard of care" - who obviously don't give a whit about Americans dying at one of the highest rates in the world:
https://www.covid-19forum.org/index.php?topic=390.0

Billions of doses of Ivermectin have been manufactured and sold all over the world and it has a well known safety profile for use in humans for over 30 years (though cautioned against for pregnant or lactating women). Upon learning of its stunning efficacy for treating COVID-19, it would be a surprise if a doctor would then hesitate to prescribe/treat with it, including as prophylaxis for high risk patients.

I would go as far as to say that if a doctor knows about it, and does not prescribe it to a COVID-19 patient, it's possible he could be more exposed to wrongful death or medical malpractice lawsuits than if he didn't. Unless practicing inside the "standard of care", makes him absolutely exempt, which I doubt.

Again Albert, welcome to the forum!
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Thank you for sharing this extremely important information for everyone to know. The problem is how are you going to get CDC, FDA, NIH, and NIAID to approve and recommend ivermectin for Covid-19 treatment. Without their approval, doctors are not allowed to prescribe ivermectin.

By the way, how did you find us since we are cast into outer darkness on Google and shadow banned on FaceBook? Was it a link on brandnewtube or conservativetreehouse?
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"Ivermectin treatment is a ‘real killer of coronavirus’: Professor Thomas Borody
5,000 fold reduction in volume of virus within 48 hours
" (in vitro)

For Ivermectin studies go to the early and late study categories in this forum.

https://www.youtube.com/watch?v=F6A6RFDprIs
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Ivermectin for the COVID-19 chronic "long haulers"?

https://youtu.be/da76aR7U41U
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The post that had been in this space was moved to a more prominent position at the top of an earlier post here:
https://www.covid-19forum.org/index.php?topic=461.msg650#msg650
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« Last Edit: March 22, 2021, 02:46:55 PM by admin »
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"Slovakia Becomes the First EU Nation to Formally Approve Ivermectin for Both Prophylaxis and Treatment for COVID-19 Patients

By TrialSite Staff January 28, 2021

The Slovakia Republic’s Minister of Health has formerly registered Ivermectin as an approved prophylaxis and treatment for SARS-CoV-2, the virus behind COVID-19. In breaking news, the authorization occurred yesterday as doctors received the news that they could proceed with formally authorized prescriptions both in hospitals and outpatient. On January 26, Health Minister Marek Krajci granted a permit for the unregistered drug as the drug has already been in use on a compassionate basis over the past half year. TrialSite interviewed Ondrej Halgas, a researcher from University of Toronto and originally from Slovakia. Halgas has been actively involved with a network organizing and lobbying for the drug’s approval during the pandemic. This landlocked Eastern European nation of 5.4 million people, a member of the European Union since 2004, just made history."

more
https://trialsitenews.com/slovakia-becomes-the-first-eu-nation-to-formally-approve-ivermectin-for-both-prophylaxis-and-treatment-for-covid-19-patients/
______________________________________________

"Belize, a Central American nation, has joined a small but growing list of jurisdictions where the use of Ivermectin is now authorized or officially allowed for treating SARS-CoV-2, the virus behind COVID-19.  Just recently, Acting Director of Health Services for Belize’s Ministry of Health, Dr. Melissa Diaz-Musa explained the situation to local media. What triggered this decision? Well, in the recent interview it apparently is a decision based on what authorities there deem mounting evidence from a series of studies (case series, observational and a handful of actual randomized trials), significantly high safety profile, effectivity and cost. She also pointed to a growing number of established protocols, even ones discussed in America. In what will undoubtedly be deemed a controversial move by key players in research and regulatory power centers in the U.S. and Europe, the move basically represents a sort of pragmatic survival as a Latin American developing nation seeks answers to the pandemic. But TrialSite has monitored a chorus heard from an exponentially growing number of observers supporting the embrace of this drug for research purposes targeting COVID-19 at least. Purportedly taken by over a billion people annually to fight parasites of various types, TrialSite analysts and network picks up growing chatter that a looming shortage of the drug, representing surging demand, could soon be a reality. What is the truth behind Ivermectin and its effectiveness and safety targeting COVID-19? As Operation Warp Speed just allocated another $356 million for yet another novel experimental biological therapy targeting COVID-19 (now over $2.5 billion just for therapies), should there be more attention as well placed on the repurposing of existing approved therapies?

Accumulating Evidence Should Trigger Interest in Research
https://trialsitenews.com/central-american-nation-of-belize-authorizes-use-of-ivermectin-for-covid-19/
« Last Edit: March 22, 2021, 03:28:57 PM by admin »
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https://uncanceled.news/philippine-doctor-defends-use-of-ivermectin-says-clinical-studies-show-it-is-89-effective-against-the-coronavirus/

"A doctor from the Philippines is defending the use of ivermectin for preventing and treating Wuhan coronavirus (COVID-19) infection despite attempts by the country’s regulatory authorities to restrict its use. In an interview with Philippine television station ABS-CBN, orthopedic surgeon and President of the Concerned Doctors and Citizens of the Philippines, Dr. Benigno Agbayani cited 80 clinical studies that show the anti-parasitic drug is 89 percent effective at preventing infection and 80 percent effective at treating COVID-19."
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In a Feb 4, 2021 article Merck warns against use of their own, time-tested drug that has proven itself to be one of the safest drugs on the planet over the last 35 years, while remaining the most efficacious drug in treatment of COVID-19.

"Merck warns against using anti-parasite drug to treat COVID-19"
"Merck added that there was a concerning lack of safety data in the majority of studies testing ivermectin to treat COVID-19 and cautioned against the use of the drug beyond its use as an anti-parasitic. (Reporting by Amruta Khandekar; Editing by Ramakrishnan M.)"

Which is of course a lie of monumental proportions, since none of the studies indicated harm from this wonder drug for COVID-19, as demonstrated by physicians that have been curing COVID with it since at least April of 2020 with near 100% success in early treatment, and even up to 50% reduction of mortality in later hospitalized patients. There is an obvious reason that some poor African countries that have had widespread historical use of ivermectin, have enjoyed less than 1% of COVID deaths that we have had in the U.S.

But of course as usual, Big Pharma's media lackeys and alphabet bureaucracies had the unmitigated gall to quickly jump on and parrot these lies, in spite of the available information that shows ivermectin has proven itself to be an up to 100% effective cure for COVID-19 for well over a year now.
https://www.covid-19forum.org/index.php?topic=461.0

The treating physicians experiences should suffice to demonstrate to any sane person that up to 100% cure in early outpatient treatment is better than the average 5-10% mortality from COVID in elderly and high-risk individuals.
Here's the science:  https://c19ivermectin.com/
The extensive proof as reported by treating physicians is in the original post.

So why would Merck try to kill their own Nobel Prize winning OFF-PATENT drug that has had billions of doses prescribed around the world over the last 35 years?

https://www.thestreet.com/investing/merck-reaches-covid-therapy-deal-under-operation-warp-speed
"Merck Reaches $350 Million COVID Therapy Deal Under Operation Warp Speed

Merck will supply up to 100,000 doses of the developing COVID treatment it acquired last month from Oncolmmune in a deal with the U.S. government's Operation Warp Speed.
Martin Baccardax Dec 23, 2020 9:39 AM EST

Merck & Co.  (MRK) - Get Report said Wednesday that it reached a $350 million agreement with the U.S. government to supply its developing coronavirus treatment as part of Operation Warp Speed.

Merck said the agreement would allow for the development, manufacture and distribution of the treatment, which is will named MK-7110, following its Emergency Use Authorization approval from the Food & Drug Administration. Merck acquired the treatment last month through its $425 million takeover of Rockville, Maryland-based Oncolmmune, which said its developing therapy can sharply reduce the risk of death or respiratory failure in patients suffering from severe forms of COVID-19.

The deal would pay Merck around $356 million for the manufacture and supply of between 60,000 and 100,000 doses of MK-7110 by then end of June, the company said."

So first the NIH creates the group of severely ill patients, by its failure to recommend effective early treatment, so corporate criminals like those at Merck and Gilead can profit off of the dying that they created.
« Last Edit: June 28, 2021, 09:10:12 AM by admin »
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https://video.foxnews.com/v/6259740044001?playlist_id=3386055101001#sp=show-clips

Sen. Johnson and Dr. Pierre Kory on the impact of censorship in fight against COVID-19
Jun. 20, 2021 - 16:10 - Sen. Ron Johnson, R-Wisc., and Dr. Pierre Kory, Chief Medical Officer of the FLCCC Alliance, weigh in on 'Sunday Morning Futures.'
___________________________________

https://www.nature.com/articles/s41429-020-0336-z

Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen

"The antiviral effects of ivermectin on RNA viruses

COVID-19

In a recent in vitro study, the Vero/hSLAM cells infected with the SARS-CoV-2 or COVID-19 virus were exposed to 5 µM ivermectin in 48 h, and a 5000-fold reduction in viral RNA compared with control was found [15]. The results showed that treatment with ivermectin effectively kills almost all viral particles within 48 h. The study was the first to assess the antiviral effect of ivermectin on COVID-19. The authors acknowledged that the drug may have antiviral effects by inhibiting the importin (IMP) α/β receptor, which is responsible for transmitting viral proteins into the host cell nucleus. The authors proposed human studies to confirm the potential benefits of ivermectin in the treatment of COVID-19. Although this study was the first to confirm the antiviral effect of ivermectin on COVID-19 [15], other studies examined the antiviral effects of the drug on both RNA and DNA viruses, which are summarized in Table 1."

 "Several studies reported antiviral effects of ivermectin on RNA viruses such as Zika, dengue, yellow fever, West Nile, Hendra, Newcastle, Venezuelan equine encephalitis, chikungunya, Semliki Forest, Sindbis, Avian influenza A, Porcine Reproductive and Respiratory Syndrome, Human immunodeficiency virus type 1, and severe acute respiratory syndrome coronavirus 2. Furthermore, there are some studies showing antiviral effects of ivermectin against DNA viruses such as Equine herpes type 1, BK polyomavirus, pseudorabies, porcine circovirus 2, and bovine herpesvirus 1."

https://www.nature.com/articles/s41429-020-0336-z
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The BIG LIE about ivermectin overdosing, with headlines like "Dewormer overdoses overwhelm Oklahoma hospitals", as straightened out by the place where it was supposed to have happened.

With "journalism" shilling for Big Pharma the way it is today, and suppressing 99+% effective cures with cheap generic drugs, no surprise the lie was repeated by New York Daily News, Newsweek, The Guardian, Insider and Rolling Stone.

For the truth: https://nhssequoyah.com/

"Message from the administration of Northeastern Health System - Sequoyah:

Although Dr. Jason McElyea is not an employee of NHS Sequoyah, he is affiliated with a medical staffing group that provides coverage for our emergency room.

With that said, Dr. McElyea has not worked at our Sallisaw location in over 2 months.

NHS Sequoyah has not treated any patients due to complications related to taking ivermectin. This includes not treating any patients for ivermectin overdose.

All patients who have visited our emergency room have received medical attention as appropriate. Our hospital has not had to turn away any patients seeking emergency care.

We want to reassure our community that our staff is working hard to provide quality healthcare to all patients. We appreciate the opportunity to clarify this issue and as always, we value our community’s support."

https://youtu.be/C_QiJ48IyWg
« Last Edit: September 06, 2021, 12:40:05 PM by admin »
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El Salvador offers free ivermectin to citizens
« Reply #21 on: September 21, 2021, 07:27:37 AM »
https://www.worldtribune.com/media-mum-on-indias-ivermectin-success-story-el-salvador-offers-it-free-to-citizens/

"Media mum on India’s Ivermectin success story; El Salvador offers it free to citizens

By Editor Two on September 19, 2021

by WorldTribune Staff, September 19, 2021

Big Media is continuing its blackout on how India has put Ivermectin to use in the treatment and prevention of Covid-19 to great success.

Meanwhile, the government of El Salvador is now including Ivermectin in its packets of treatments for Covid that are being given freely to citizens.

On Aug. 15, the Ivermectin-using state of Delhi in India recorded only 53 new cases and zero deaths.

Kerala, which is not using Ivermectin, accounted for 18,582 of India’s 32,937 new cases and 102 of India’s 417 new deaths as reported on Aug. 15. In comparison, Uttar Pradesh, with almost eight times as many inhabitants as Kerala, had only 30 new cases and one death.

“The New York Times reported India’s colossal drop in Covid cases was unexplainable, while the BBC declared that Kerala’s rise was also a mystery,” Dr. Justus R. Hope noted in an analysis for The Desert Review. “While new cases of COVID in Uttar Pradesh are rare as million-dollar lottery tickets, in Kerala, a tiny state located in southern India, new daily cases are the same as the United States, nearly one case per thousand. Yet, as we have seen in this series, there has been a curious media blackout on India’s overall success against Covid.”

Uttar Pradesh was the first state in India to introduce large-scale prophylactic and therapeutic use of Ivermectin.

“In May-June 2020, a team at Agra led by Dr. Anshul Pareek, administered Ivermectin to all RRT team members in the district on an experimental basis. It was observed that NONE OF THEM developed COVID-19 despite being in daily contact with patients who had tested positive for the virus,” Uttar Pradesh State Surveillance Officer Vikssendu Agrawal said.

Dr. Hope noted that Uttar Pradesh “has a policy of treating ALL the contacts of an infected patient prophylactically with Ivermectin. In other words, in Uttar Pradesh, everyone in the house gets Ivermectin treatment even if only one is infected. Ivermectin is known to reduce mortality in infected and dramatically lowers the viral load, thereby helping reduce the spread of the virus to others.”

Kerala ranks in the top five most vaccinated of India’s 29 states.

“Viral loads of the vaccinated are just as high as those of the unvaccinated as the CDC has admitted,” Dr. Hope noted. “If a vaccinated person spreads the virus while someone on Ivermectin does not, that would explain Kerala’s epic failure. The lesson? Ivermectin can make up for the low use of vaccination. However, vaccination cannot make up for the low use of Ivermectin.”

In El Salvador, the government is including Ivermectin for free to citizens as a Covid treatment along with ivermectin vitamin C, D, zinc & aspirin for blood-clots.

    El Salvador is INCREDIBLE pic.twitter.com/0411jgXKu9

    — Source_BTC (@Source_33_) September 16, 2021
______________________________________________

 https://anticoercion.org/posts/el-salvador/

"El Salvador gives out free medication for covid

Thursday, September 16, 2021

Do we have a death-wish in Australia?

Australia has put Ivermectin on the banned drug list. Doctors are forbidden from prescribing it and you as the patient have no say in the matter."

Same death wish as the genocidal maniac Fauci and U.S. government illness agencies.
« Last Edit: September 21, 2021, 09:59:26 AM by admin »
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« Last Edit: October 07, 2021, 10:55:53 AM by admin »
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The 22 mechanisms of action of ivermectin against SARS-CoV2 virus.
« Reply #23 on: October 14, 2021, 09:09:17 AM »
Published in science Journal List - Nature Public Health Emergency Collection
https://www.nature.com/articles/s41429-021-00491-6

The 22 mechanisms of action of ivermectin against SARS-CoV2 virus.

"Fig. 1
A schematic of the key cellular and biomolecular interactions between Ivermectin, host cell, and SARS-CoV-2 in COVID-19 pathogenesis and prevention of complications.

Ivermectin; IVM (red block) inhibits and disrupts binding of the SARS-CoV-2 S protein at the ACE-2 receptors (green). The green dotted lines depict activation pathways and the red dotted lines depict the inhibition pathways. The TLR-4 receptors are directly activated by SARS-CoV-2 and also by LPS mediated activation (seen during ICU settings) causing activation of NF-Kb pathway and MAP3 Kinases leading to increased intranuclear gene expression for proinflammatory cytokines and chemokines (responsible for cytokine storm) and NO release (responsible for blood vessel dilatation, fluid leak, low blood pressure, ARDS and sepsis). The NF-Kb and STAT-3 pathway activation is central to the pathogenesis and sequelae of COVID-19. STAT-3 physically binds to PAK-1 and increases IL-6 transcription. The annexin A2 at the cell surface converts plasminogen; PLG to plasmin under the presence of t-PA. Plasmin triggers activation and nuclear translocation of STAT-3. An upregulation of STAT-3 stimulates hyaluronan synthase-2 in the lung cells causing hyaluronan deposition leading to diffuse alveolar damage and hypoxia. STAT-3 also directly activates TGF-beta initiating pulmonary fibrosis; a typical characteristic of SARS-COV-2 lung pathology. The damaged type 2 cells express PAI-1 and an already hypoxic state also causes an upregulation of PAI (through Hypoxic inducible factor-1) along with direct stimulation by STAT-3. Simultaneous STAT-3 and PAI-1 activation inhibits t-PA and urokinase-type plasminogen activator leading to thrombi formation. Also, the SARS-CoV-2 spike protein binds to the CD147 on red blood cells and causes clumping. IVM in turn, binds to SARS-CoV-2 Spike protein and hence prevents clumping. T cell lymphopenia in COVID-19 can also be attributed to the direct activation of PD-L1 receptors on endothelial cells by STAT-3. IVM directly inhibits the NF-kb pathway, STAT-3, and indirectly inhibits PAK-1 by increasing its ubiquitin-mediated degradation. The natural antiviral response of a cell is through interferon regulatory genes and viral RNA mediated activation of TLR-3 and TLR7/8- Myd88 activation of transcription of interferon-regulator (IRF) family. For a virus to establish an infection, this antiviral response needs to be inhibited by blocking interferon production. The proteins such as importin and KPNA mediate nuclear transport of viral protein and subsequent IFN signaling. The SARS-CoV-2 proteins (ORF-3a, NSP-1, and ORF-6) directly block IFN signaling causing the surrounding cells to become unsuspecting victims of the infection. IVM inhibits both importin a-b (green) as well as the KPNA-1 receptors (brown) causing natural antiviral IFN release. IVM also inhibits viral RdrP, responsible for viral replication. IVM Ivermectin, ACE-2 angiotensin-converting-enzyme 2, LPS Lipopolysaccharide, TLR Toll-like receptor, t-PA tissue-like plasminogen activator, PLG Plasminogen, IMPab Importin alpha-beta, Rdrp RNA dependant RNA polymerase, KPNA-1 Karyopherin Subunit Alpha 1, NF-kB nuclear factor kappa-light-chain-enhancer of activated B cells, Map3Kinases Mitogen-activated Kinases, PAK-1 P21 Activated Kinase 1, STAT-3 Signal transducer and activator of transcription 3, PAI-1 Plasminogen activator inhibitor-1, HIF-1 Hypoxia-Inducible Factor"



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How does Big Pharma's FDA characterize the safe, cheap, generic, Nobel Prize winning ivermectin that is on the WHO list of essential medications, that has enjoyed a stunningly safe profile for use in humans for over 40 years, that the WHO even suggests: "WHO Bulletin-Mass treatment with ivermectin underutilized public health strategy"?
That when used that way eliminated COVID among 230 million residents in the Indian state of Uttar Pradesh.
Secret formula eradicates COVID in India state of 230 million people

Billions of doses have been taken over 40 years and it is available over the counter in many countries, that in the U.S. is prescribed routinely for scabies, head lice, rosacea, etc. etc.

A wonder drug boasting 22 mechanisms of action against the SARS-CoV-2 virus:
https://www.covid-19forum.org/index.php?topic=1229.0

Here's how Big Pharma's FDA weighs in on the subject, with their inference being that ivermectin is for horses not for people even though has been approved by the FDA for use in humans for nearly 40 years. That should tell you everything you need to know about what kind of information you will get from the FDA. PURE PROPAGANDA to advance Big Pharma and global genocide:
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19

"Why You Should Not Use Ivermectin to Treat or Prevent COVID-19



Their big reason?
"The FDA has not authorized or approved ivermectin for the treatment or prevention of COVID-19 in people or animals. Ivermectin has not been shown to be safe or effective for these indications."


On their Twitter feed they had the unmitigated gall to post the following insulting and homicidal tweet - in regard to this medication that has saved tens to hundreds of millions of lives from COVID-19:
“You are not a horse. You are not a cow. Seriously, y’all. Stop it.” Even though 3.5 billion doses of ivermectin have been taken by humans over the last 35 years.

Nor will they approve it because it is generic and not patentable (and sells for as little as 2 cents per dose) so there is no collective fortune to be made by their masters. Regarding their outright abject lie about safety, billions of doses have been taken over nearly 40 years and the WHO suggests that mass distribution of ivermectin is an underutilized public health strategegy. Regarding their big lie about it not being effective, the science is in and has been for a very long time, let alone eliminating COVID-19 from every population that has engaged in mass distribution or a "test and treat" program. Like eradicating COVID-19 among the 230 million people of Uttar Pradesh India.
https://www.covid-19forum.org/index.php?topic=1068.0

According to a science paper published on the NIH's own site:
https://pubmed.ncbi.nlm.nih.gov/32533071/
"Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen

Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses. In this comprehensive systematic review, antiviral effects of ivermectin are summarized including in vitro and in vivo studies over the past 50 years. Several studies reported antiviral effects of ivermectin on RNA viruses such as Zika, dengue, yellow fever, West Nile, Hendra, Newcastle, Venezuelan equine encephalitis, chikungunya, Semliki Forest, Sindbis, Avian influenza A, Porcine Reproductive and Respiratory Syndrome, Human immunodeficiency virus type 1, and severe acute respiratory syndrome coronavirus 2. Furthermore, there are some studies showing antiviral effects of ivermectin against DNA viruses such as Equine herpes type 1, BK polyomavirus, pseudorabies, porcine circovirus 2, and bovine herpesvirus 1. Ivermectin plays a role in several biological mechanisms, therefore it could serve as a potential candidate in the treatment of a wide range of viruses including COVID-19 as well as other types of positive-sense single-stranded RNA viruses. In vivo studies of animal models revealed a broad range of antiviral effects of ivermectin, however, clinical trials are necessary to appraise the potential efficacy of ivermectin in clinical setting."

Tons of studies proving its efficacy from early treatment through late hospitalization. And most of those studies were designed to make it appear less effective, since it is otherwise near 100% effective even in the elderly and high-risk individuals when used in early treatment with multi-drug/nutraceutical protocols.
151 ivermectin COVID studies, 103 peer reviewed, 81 comparing treatment &control
https://c19ivermectin.com/

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« Last Edit: December 24, 2021, 10:26:25 PM by admin »
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"Florida Doctor: Families Sneak Ivermectin To Loved Ones In Hospitals With COVID-19, See Improvement"

https://www.zerohedge.com/markets/florida-doctor-families-sneak-ivermectin-loved-ones-hospitals-covid-19-see-improvement
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Drug adverse event comparison for U.S.
https://www.ronjohnson.senate.gov/services/files/A4A76F9A-9B29-4CF9-B987-F9097A3F4CB7

Here are global stats just through 9-30-21 (On billions of doses of ivermectin)


_________________________________

Regarding Tylenol:

"Conclusions
Acetaminophen-related adverse events continue to be a public health burden. Future studies with additional time points are necessary to confirm trends and determine whether recent risk mitigation efforts had a beneficial impact on acetaminophen-related adverse events."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676300/
_____________________________________

While: " Ivermectin has a wide therapeutic index and previous studies have shown doses up to 2000 mcg/kg (ie, 10 times the US Food and Drug Administration approved dose) are well tolerated and safe; the highest dose used for onchocerciasis is a single dose of 800 mcg/kg."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133431/

For various dosages of IVM for COVID, depending on state of disease development, check with FLCCC:
https://covid19criticalcare.com/wp-content/uploads/2020/11/FLCCC-Alliance-I-MASKplus-Protocol-ENGLISH.pdfhttps://covid19criticalcare.com/wp-content/uploads/2020/11/FLCCC-Alliance-I-MASKplus-Protocol-ENGLISH.pdf
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Life saved by ivermectin smuggled into the hospital embedded in chocolate bar.
https://rumble.com/vrv7sf-carol-hayes-uk-ivermectin-smuggled-in-chocolate-bar-saved-my-life.html
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Ivermectin, a potential anticancer drug derived from an antiparasitic drug
« Reply #29 on: February 22, 2022, 03:33:35 PM »
Truly a God-given wonder drug, ivermectin is also useful in treatment of cancer.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/

"Pharmacol Res. 2021 Jan; 163: 105207.
Published online 2020 Sep 21. doi: 10.1016/j.phrs.2020.105207
PMCID: PMC7505114
PMID: 32971268

Ivermectin, a potential anticancer drug derived from an antiparasitic drug

Mingyang Tang,a,b,1 Xiaodong Hu,c,1 Yi Wang,a,d Xin Yao,a,d Wei Zhang,a,b Chenying Yu,a,b Fuying Cheng,a,b Jiangyan Li,a,d and Qiang Fanga,d,e,*

Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. On the other hand, ivermectin promotes programmed cancer cell death, including apoptosis, autophagy and pyroptosis. Ivermectin induces apoptosis and autophagy is mutually regulated. Interestingly, ivermectin can also inhibit tumor stem cells and reverse multidrug resistance and exerts the optimal effect when used in combination with other chemotherapy drugs.

Abstract

Ivermectin is a macrolide antiparasitic drug with a 16-membered ring that is widely used for the treatment of many parasitic diseases such as river blindness, elephantiasis and scabies. Satoshi ōmura and William C. Campbell won the 2015 Nobel Prize in Physiology or Medicine for the discovery of the excellent efficacy of ivermectin against parasitic diseases. Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways. This suggests that ivermectin may be an anticancer drug with great potential. Here, we reviewed the related mechanisms by which ivermectin inhibited the development of different cancers and promoted programmed cell death and discussed the prospects for the clinical application of ivermectin as an anticancer drug for neoplasm therapy.

1. Introduction

Ivermectin(IVM) is a macrolide antiparasitic drug with a 16-membered ring derived from avermectin that is composed of 80% 22,23-dihydroavermectin-B1a and 20% 22,23-dihydroavermectin-B1b [1]. In addition to IVM, the current avermectin family members include selamectin, doramectin and moxidectin [[2], [3], [4], [5]] (Fig. 1 ). IVM is currently the most successful avermectin family drug and was approved by the FDA for use in humans in 1978 [6]. It has a good effect on the treatment of parasitic diseases such as river blindness, elephantiasis, and scabies. The discoverers of IVM, Japanese scientist Satoshi ōmura and Irish scientist William C. Campbell, won the Nobel Prize in Physiology or Medicine in 2015 [7,8]. IVM activates glutamate-gated chloride channels in the parasite, causing a large amount of chloride ion influx and neuronal hyperpolarization, thereby leading to the release of gamma-aminobutyric acid (GABA) to destroy nerves, and the nerve transmission of muscle cells induces the paralysis of somatic muscles to kill parasites [9,10]. IVM has also shown beneficial effects against other parasitic diseases, such as malaria [11,12], trypanosomiasis [13], schistosomiasis [14], trichinosis [15] and leishmaniasis [16].

IVM not only has strong effects on parasites but also has potential antiviral effects. IVM can inhibit the replication of flavivirus by targeting the NS3 helicase [17]; it also blocks the nuclear transport of viral proteins by acting on α/β-mediated nuclear transport and exerts antiviral activity against the HIV-1 and dengue viruses [18]. Recent studies have also pointed out that it has a promising inhibitory effect on the SARS-CoV-2 virus, which has caused a global outbreak in 2020 [19]. In addition, IVM shows potential for clinical application in asthma [20] and neurological diseases [21]. Recently scientists have discovered that IVM has a strong anticancer effect.

Since the first report that IVM could reverse tumor multidrug resistance (MDR) in 1996 [22], a few relevant studies have emphasized the potential use of IVM as a new cancer

treatment [[23], [24], [25], [26], [27]]. Despite the large number of related studies, there are still some key issues that have not been resolved. First of all, the specific mechanism of IVM-mediated cytotoxicity in tumor cells is unclear; it may be related to the effect of IVM on various signaling pathways, but it is not very clear overall. Second, IVM seems to induce mixed cell death in tumor cells, which is also a controversial issue. Therefore, this review summarized the latest findings on the anticancer effect of IVM and discussed the mechanism of the inhibition of tumor proliferation and the way that IVM induces tumor programmed cell death to provide a theoretical basis for the use of IVM as a potential anticancer drug. As the cost of the research and development of new anticancer drugs continues to increase, drug repositioning has become increasingly important. Drug repositioning refers to the development of new drug indications that have been approved for clinical use [28]. For some older drugs that are widely used for their original indications and have clinical data and safety information, drug repositioning allows them to be developed via a cheaper and faster cycle and to be used more effectively in clinical use clinically [29]. Here, we systematically summarized the anticancer effect and mechanism of IVM, which is of great significance for the repositioning of IVM for cancer treatment.

2. The role of IVM in different cancers
2.1. Breast cancer

Breast cancer is a malignant tumor produced by gene mutation in breast epithelial cells caused by multiple carcinogens. The incidence of breast cancer has increased each year, and it has become one of the female malignant tumors with the highest incidence in globally. On average, a new case is diagnosed every 18 seconds worldwide [30,31]. After treatment with IVM, the proliferation of multiple breast cancer cell lines including MCF-7, MDA-MB-231 and MCF-10 was significantly reduced. The mechanism involved the inhibition by IVM of the Akt/mTOR pathway to induce autophagy and p-21-activated kinase 1(PAK1)was the target of IVM for breast cancer [32]. Furthermore, Diao’s study showed that IVM could inhibit the proliferation of the canine breast tumor cell lines CMT7364 and CIPp by blocking the cell cycle without increasing apoptosis, and the mechanism of IVM may be related to the inhibition of the Wnt pathway [33].

Triple-negative breast cancer (TNBC) refers to cancer that is negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2(HER2) and is the most aggressive subtype of breast cancer with the worst prognosis. In addition, there is also no clinically applicable therapeutic drug currently [34,35]. A drug screening study of TNBC showed that IVM could be used as a SIN3-interaction domain (SID) mimic to selectively block the interaction between SID and paired a-helix2. In addition, IVM regulated the expression of the epithelial mesenchymal-transition (EMT) related gene E-cadherin to restore the sensitivity of TNBC cells to tamoxifen, which implies the possibility that IVM functions as an epigenetic regulator in the treatment of cancer[36].

Recent studies have also found that IVM could promote the death of tumor cells by regulating the tumor microenvironment in breast cancer. Under the stimulation of a tumor microenvironment with a high level of adenosine triphosphate (ATP) outside tumor cells, IVM could enhance the P2 × 4/ P2 × 7/Pannexin-1 mediated release of high mobility group box-1 protein (HMGB1) [37]. However, the release of a large amount of HMGB1 into the extracellular environment will promote immune cell-mediated immunogenic death and inflammatory reactions, which will have an inhibitory effect on the growth of tumor cells. Therefore, we believe that the anticancer effect of IVM is not limited to cytotoxicity, but also involves the regulation of the tumor microenvironment. IVM regulates the tumor microenvironment and mediates immunogenic cell death, which may be a new direction for research exploring anticancer mechanisms in the future.
2.2. Digestive system cancer

Gastric cancer is one of the most common malignant tumors worldwide. In the past year, more than one million patients with gastric cancer have been diagnosed worldwide [38]. Nambara’s study showed that IVM could significantly inhibit the proliferation of gastric cancer cells in vivo and in vitro and that the inhibitory effect of IVM depended on the expression of Yes-associated protein 1(YAP1)[39]. The gastric cancer cell lines MKN1 and SH-10-TC have higher YAP1 expression than MKN7 and MKN28 cells, so MKN1 and SH-10-TC cells are sensitive to IVM, while MKN7 and MKN28 are not sensitive to IVM.YAP1 plays an oncogenic role in tumorigenesis, indicating the possibility of the use of IVM as a YAP1 inhibitor for cancer treatment [40].

In a study that screened Wnt pathway inhibitors, IVM inhibited the proliferation of multiple cancers, including the colorectal cancer cell lines CC14, CC36, DLD1, and Ls174 T, and promoted apoptosis by blocking the Wnt pathway [41]. After intervention with IVM, the expression of caspase-3 in DLD1 and Ls174 T cells increased, indicating that IVM has an apoptosis-inducing effect and inhibits the expression of the downstream genes AXIN2, LGR5, and ASCL2 in the Wnt/β-catenin pathway. However, the exact molecular target of IVM that affects the Wnt/β-catenin pathway remains to be explored.

Hepatocellular carcinoma is the fourth leading cause of cancer death worldwide. Approximately 80% of cases of liver cancer are caused by hepatitis B virus (HBV) and hepatitis C virus (HCV) infection [42]. IVM could inhibit the development of hepatocellular carcinoma by blocking YAP1 activity in spontaneous liver cancer Mob1b-/- mice [43].Cholangiocarcinoma is a malignant tumor that originates in the bile duct inside and outside the liver. Intuyod's experiment found that IVM inhibited the proliferation of KKU214 cholangiocarcinoma cells in a dose- and time-dependent manner [44]. IVM halted the cell cycle in S phase and promoted apoptosis. Surprisingly, gemcitabine-resistant KKU214 cells showed high sensitivity to IVM, which suggested that IVM shows potential for the treatment of tumors that are resistant to conventional chemotherapy drugs.
2.3. Urinary system cancer

Renal cell carcinoma is a fatal malignant tumor of the urinary system derived from renal tubular epithelial cells. Its morbidity has increased by an average of 2% annually worldwide and the clinical treatment effect is not satisfactory [[45], [46], [47]]. Experiments confirmed that IVM could significantly inhibit the proliferation of five renal cell carcinoma cell lines without affecting the proliferation of normal kidney cells, and its mechanism may be related to the induction of mitochondrial dysfunction [48]. IVM could significantly reduce the mitochondrial membrane potential and inhibit mitochondrial respiration and ATP production. The presence of the mitochondrial fuel acetyl-L-carnitine (ALCAR), and the antioxidant N-acetyl-L-cysteine (NAC), could reverse IVM-induced inhibition. In animal experiments, the immunohistochemical results for IVM-treated tumor tissues showed that the expression of the mitochondrial stress marker HEL was significantly increased, and the results were consistent with those of the cell experiments.

Prostate cancer is a malignant tumor derived from prostate epithelial cells, and its morbidity is second only to that of lung cancer among men in Western countries [49]. In Nappi's experiment, it was found that IVM could enhance the drug activity of the anti-androgen drug enzalutamide in the prostate cancer cell line LNCaP and reverse the resistance of the prostate cancer cell line PC3 to docetaxel [50]. Interestingly, IVM also restored the sensitivity of the triple-negative breast cancer to the anti-estrogen drug tamoxifen [36], which also implies the potential for IVM to be used in endocrine therapy. Moreover, IVM was also found to have a good inhibitory effect on the prostate cancer cell line DU145 [51].
2.4. Hematological cancer

Leukemia is a type of malignant clonal disease caused by abnormal hematopoietic stem cells [52]. In an experiment designed to screen potential drugs for the treatment of leukemia, IVM preferentially killed leukemia cells at low concentrations without affecting normal hematopoietic cells [51]. The mechanism was related to the increase in the influx of chloride ions into the cell by IVM, resulting in hyperpolarization of the plasma membrane and induction of reactive oxygen species (ROS) production. It was also proven that IVM has a synergistic effect with cytarabine and daunorubicin on the treatment of leukemia. Wang's experiment found that IVM could selectively induce mitochondrial dysfunction and oxidative stress, causing chronic myeloid leukemia K562 cells to undergo increased caspase-dependent apoptosis compared with normal bone marrow cells [53]. It was also confirmed that IVM inhibited tumor growth in a dose-dependent manner, and dasatinib had improved efficacy.
2.5. Reproductive system cancer

Cervical cancer is one of the most common gynecological malignancies, resulting in approximately 530,000 new cases and 270,000 deaths worldwide each year. The majority of cervical cancers are caused by human papillomavirus (HPV) infection [54,55]. IVM has been proven to significantly inhibit the proliferation and migration of HeLa cells and promote apoptosis [56]. After intervention with IVM, the cell cycle of HeLa cells was blocked at the G1/S phase, and the cells showed typical morphological changes related to apoptosis.

Ovarian cancer is a malignant cancer that lacks early clinical symptoms and has a poor therapeutic response. The 5-year survival rate after diagnosis is approximately 47% [27,57]. In a study by Hashimoto, it found that IVM inhibited the proliferation of various ovarian cancer cell lines, and the mechanism was related to the inhibition of PAK1 kinase [58]. In research to screen potential targets for the treatment of ovarian cancer through the use of an shRNA library and a CRISPR/Cas9 library, the oncogene KPNB1 was detected. IVM could block the cell cycle and induce cell apoptosis through a KPNB1-dependent mechanism in ovarian cancer [59]. Interestingly, IVM and paclitaxel have a synergistic effect on ovarian cancer, and combined treatment in in vivo experiments almost completely inhibited tumor growth. Furthermore, according to a report by Zhang, IVM can enhance the efficacy of cisplatin to improve the treatment of epithelial ovarian cancer, and the mechanism is related to the inhibition of the Akt/mTOR pathway [60].
2.6. Brain glioma

Glioma is the most common cerebral tumor and approximately 100,000 people worldwide are diagnosed with glioma every year. Glioblastoma is the deadliest glioma, with a median survival time of only 14-17 months [61,62]. Experiments showed that IVM inhibited the proliferation of human glioblastoma U87 and T98 G cells in a dose-dependent manner and induced apoptosis in a caspase-dependent manner [63]. This was related to the induction of mitochondrial dysfunction and oxidative stress. Moreover, IVM could induce apoptosis of human brain microvascular endothelial cells and significantly inhibit angiogenesis. These results showed that IVM had the potential to resist tumor angiogenesis and tumor metastasis. In another study, IVM inhibited the proliferation of U251 and C6 glioma cells by inhibiting the Akt/mTOR pathway [64].

In gliomas, miR-21 can regulate the Ras/MAPK signaling pathway and enhance its effects on proliferation and invasion [65]. The DDX23 helicase activity affects the expression of miR-12 [66]. IVM could inhibit the DDX23/miR-12 signaling pathway by affecting the activity of DDX23 helicase, thereby inhibiting malignant biological behaviors. This indicated that IVM may be a potential RNA helicase inhibitor and a new agent for of tumor treatment. However, here, we must emphasize that because IVM cannot effectively pass the blood-brain barrier [67], the prospect of the use of IVM in the treatment of gliomas is not optimistic.
2.7. Respiratory system cancer

Nasopharyngeal carcinoma is a malignant tumor derived from epithelial cells of the nasopharyngeal mucosa. The incidence is obviously regional and familial, and Epstein-Barr virus (EBV) infection is closely related [68]. In a study that screened drugs for the treatment of nasopharyngeal cancer, IVM significantly inhibited the development of nasopharyngeal carcinoma in nude mice at doses that were not toxic to normal thymocytes [69]. In addition, IVM also had a cytotoxic effect on a variety of nasopharyngeal cancer cells in vitro, and the mechanism is related to the reduction of PAK1 kinase activity to inhibit the MAPK pathway.

Lung cancer has the highest morbidity and mortality among cancers [70]. Nishio found that IVM could significantly inhibit the proliferation of H1299 lung cancer cells by inhibiting YAP1 activity [43]. Nappi's experiment also proved that IVM combined with erlotinib to achieved a synergistic killing effect by regulating EGFR activity and in HCC827 lung cancer cells [50]. In addition, IVM could reduce the metastasis of lung cancer cells by inhibiting EMT.
2.8. Melanoma

Melanoma is the most common malignant skin tumor with a high mortality rate. Drugs targeting BRAF mutations such as vemurafenib, dabrafenib and PD-1 monoclonal antibodies, including pembrolizumab and nivolumab have greatly improved the prognosis of melanoma [71,72]. Gallardo treated melanoma cells with IVM and found that it could effectively inhibit melanoma activity [73]. Interestingly, IVM could also show activity against BRAF wild-type melanoma cells, and its combination with dapafinib could significantly increase antitumor activity. Additionally, it has been confirmed that PAK1 is the key target of IVM that mediates its anti-melanoma activity, and IVM can also significantly reduce the lung metastasis of melanoma in animal experiments. Deng found that IVM could activate the nuclear translocation of TFE3 and induce autophagy-dependent cell death by dephosphorylation of TFE3 (Ser321) in SK-MEL-28 melanoma cells [74]. However, NAC reversed the effect of IVM, which indicated that IVM increased TFE3-dependent autophagy through the ROS signaling pathway."

Much more in this extensive article:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/
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"Nebraska AG Allows Ivermectin and HCQ Prescriptions as Off-Label Medicines to Fight COVID
10-19-2021
Steve Warren

Nebraska's attorney general has said he will not discipline or prosecute physicians who prescribe controversial, off-label drugs in order to treat and prevent COVID-19 infections if they have patient consent. 

KETV reported Attorney General Doug Peterson issued his 48-page opinion Friday after receiving a question from Nebraska Department of Health and Human Services CEO Dannette Smith. She asked if doctors could face discipline or legal action under Nebraska's Uniform Credential Act (UCA) if they prescribed medications like Ivermectin and Hydroxychloroquine to fight COVID-19 in their patients.

"After receiving your question and conducting our investigation, we have found significant controversy and suspect information about potential COVID-19 treatment," Peterson wrote. He also cited numerous medical journals' articles and case studies.

"We emphasize... our office is not recommending any specific treatments for COVID-19. That is not our role," the attorney general continued.

"Rather, we address only the off-label early treatment options discussed in this opinion and conclude that the available evidence suggests they might work for some people," Peterson wrote. "Allowing physicians to consider these early treatments will free them to evaluate additional tools that could save lives, keep patients out of the hospital, and provide relief for our already strained health care system."

The FDA has cautioned against using hydroxychloroquine (HCQ) to treat COVID. Former President Trump took HCQ early in the pandemic to prevent a COVID-19 infection, then he stopped using it in May of 2020.

Other famous people said the drug worked for them. Actor Tom Hanks and his wife Rita Wilson said HCQ was useful in their recovery from the coronavirus.  Actor Daniel Dae Kim (Lost & Hawaii Five-0) claimed HCQ was the "secret weapon" that helped in his recovery from the disease.

Last year, Pastor A.R. Bernard of the Christian Cultural Center in Brooklyn, NY, talked about his harrowing bout with COVID-19 and how the drug cocktail with hydroxychloroquine and the antibiotic azithromycin saved his life.

Families Filing Lawsuits Against Hospitals, Seeking Alternative COVID Treatments for Loved Ones

At least two dozen lawsuits have been filed around the U.S., many in recent weeks, by people seeking to force hospitals to give their COVID-stricken loved ones ivermectin, a drug for parasites that has been promoted as a treatment despite a lack of conclusive evidence that it helps people with the virus.

Interest in the drug started rising toward the end of last year and the beginning of this one, when studies – some later withdrawn, in other countries – seemed to suggest ivermectin had some potential in the fight against COVID-19.

But some medical experts suggest having a court step in is not the way to practice medicine.

“The way medicine works is, they are the experts, the doctors and... the hospitals," Arthur Caplan, professor of bioethics at New York University's Grossman School of Medicine told the Associated Press. “When you go there, you’re not going to a restaurant. You don't order your own treatments."
more
https://cmsedit.cbn.com/cbnnews/health/2021/october/nebraska-ag-allows-ivermectin-and-hcq-prescriptions-as-off-label-medicines-to-fight-covid
________________________________________________

But of course patients do have to order their own treatment in the case of COVID, because so many doctors have been directly responsible for the completely unnecessary deaths of 900,000 Americans.
Compared to competent, compassionate medical professionals that have enjoyed 99+% effective treatment of elderly and high-risk patients ever since March of 2020.
MyFreeDoctor.com has treated 150,000 COVID patients with a 99.99% success rate
__________________________________________

Kansas Senate passes bill boosting access to ivermectin and weakening school vaccine rules
KCUR | By Tim Carpenter | Kansas Reflector
Published March 24, 2022 at 1:26 PM CDT

The bill would legalize the prescription of off-label COVID medications like ivermectin and hydroxychloroquine, and mandate child care facilities and K-12 public schools to accept — without inquiry or scrutiny — the religious objection of parents or guardians to vaccination of their children.

A Kansas state senator — who's being investigated by the Board of Healing Arts for alleged misconduct during the COVID-19 pandemic — voted early Thursday for legislation to legalize the prescribing by physicians and dispensing by pharmacists of medication for off-label use against the coronavirus.

The bill adopted by the Senate on a vote of 21-16 would mandate child care facilities and K-12 public schools to accept — without inquiry or scrutiny — the religious objection of parents or guardians to vaccination of their children against a collection of maladies.

Steffen, a Republican from Hutchinson and licensed anesthesiologist, had introduced legislation that would retroactively shield him and other health providers who prescribed ivermectin or hydroxychloroquine during the pandemic from investigation by regulators with the Kansas Board of Healing Arts.

In January, Steffen said he was under investigation by the BOHA. He has asserted doctors shouldn’t be limited in the range of potential treatment options in a pandemic associated with more than 8,000 deaths and 19,000 hospitalizations in Kansans.

“Thousands of Kansans and hundreds of thousands of Americans have died needlessly because mainstream academic medicine’s shutdown of effective treatment protocols,” Steffen said. “This fearful, greedy, political and incompetent shutdown of early treatment will be deemed a national tragedy in time.”

Steffen has waged a protracted war of words with public health officials and medical professionals who expressed reservations about alternative treatment of COVID-19. University of Kansas Health System submitted testimony opposing the legislation on behalf of Ascension Via Christi Health, University of Kansas School of Health Professions and University of Kansas physicians.

The retroactive provision sought by Steffen, viewed as a conflict of interest for him, was removed from the bill sent to the House. The measure would enable Kansas physicians to prescribe drugs, approved by the U.S. Food and Drug Administration, for off-label or alternative use to prevent or treat COVID-19 infection.

Both hydroxychloroquine and ivermectin were listed as eligible under the bill, which otherwise limited doctors addressing coronavirus only when it came to prescribing controlled substances.

The Senate bill also was controversial because it would amend state law to prohibit pharmacists from refusing to fill or refill prescriptions for medications based solely on knowledge or assumption the drug would be used by a patient for treatment of COVID-19."
https://www.kcur.org/politics-elections-and-government/2022-03-24/kansas-senate-passes-bill-boosting-access-to-ivermectin-and-weakening-school-vaccine-rules
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"Over-the-Counter Ivermectin? It Could Be Coming to a State Near You—Despite FDA Concerns
 The ivermectin controversy has sparked a wider debate about medical freedom.
Monday, February 7, 2022

new bill recently introduced in New Hampshire would allow residents to get ivermectin from pharmacies without first getting a prescription or approval from a doctor. The legislation, titled House Bill 1022, is still in committee, but the state House of Representatives is slated to vote on it in the coming weeks.

The purpose of the bill is to provide wider access to ivermectin for those who want to take it as a treatment for COVID-19. Thus far, the Food and Drug Administration (FDA) has not approved the drug for treating COVID-19, but many believe it is an effective treatment and are eager to have it on hand should they be infected with the virus.

Though the FDA has not weighed in on this bill in particular, the agency has made it clear that they have serious concerns about the use of ivermectin for this purpose."
Much more
https://fee.org/articles/over-the-counter-ivermectin-it-could-be-coming-to-a-state-near-you-despite-fda-concerns/
_____________________________________________

https://www.wjhl.com/news/local/over-the-counter-ivermectin-bill-headed-to-gov-lees-desk/

"Over-the-counter ivermectin bill headed to Gov. Lee’s desk
by: Amy Cockerham   
Posted: Apr 8, 2022

JOHNSON CITY, Tenn. (WJHL) – A bill that would allow ivermectin over the counter has passed in the Tennessee Senate and House and is now headed to Gov. Bill Lee’s desk.

The drug is originally used to treat roundworms or different parasites, but now some are using it to treat COVID-19.

The Compounding Lab in Johnson City fulfills prescriptions for both humans and animals. They sell ivermectin for people and said they’ve seen a big demand for the drug over the course of the pandemic.

“We’ve treated thousands and thousands of people, and we’ve seen people get better,” Dr. Josh Harrison with The Compounding Lab said. “We’ve seen people do well on it.”
Bill that would allow ivermectin to be sold over-the-counter in TN passes Senate

Dr. Harrison said personally he supports the bill and believes in the science behind the medicine.

“The COVID virus is trying to replicate it, it has to bind to certain sites and there are different proteins involved but it stops that at multiple sites so you see a huge decrease in viral load,” Dr. Harrison said.

Not all medical professionals agree that the drug is effective against COVID-19, in fact, the FDA has advised against it. According to the FDA, ivermectin tablets have been approved “at very specific doses” for the treatment of some parasitic worms, as well as a topical formula for lice and certain skin conditions. However, the FDA reports that data does not suggest ivermectin is effective against COVID-19, with trials related to using it as a treatment remain ongoing."
https://www.wjhl.com/news/local/over-the-counter-ivermectin-bill-headed-to-gov-lees-desk/
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https://makismd.substack.com/p/ivermectin-and-cancer-it-has-at-least

"IVERMECTIN and CANCER, it has at least 15 anti-cancer mechanisms of action. Can Ivermectin Treat COVID-19 mRNA Vaccine Induced Turbo Cancers? - 9 Ivermectin papers reviewed
Dr. William Makis MD
Oct 2, 2023

Papers reviewed:

    2023 Sep.23 - Man-Yuan Li et al - Ivermectin induces nonprotective autophagy by downregulating PAK1 and apoptosis in lung adenocarcinoma cells

    2023 May - Samy et al - Eprinomectin: a derivative of ivermectin suppresses growth and metastatic phenotypes of prostate cancer cells by targeting the β-catenin signaling pathway

    2022 Nov - Lotfalizadeh et al - The Anticancer potential of Ivermectin: Mechanisms of action and therapeutic implications

    2022 Oct - Jian Liu et al - Progress in Understanding the Molecular Mechanisms Underlying the Antitumour Effects of Ivermectin

    2022 Jun - Daeun Lee et al - Ivermectin suppresses pancreatic cancer via mitochondria dysfunction

    2021 Aug - Shican Zhou et al - Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth

    2021 Jan - Mingyang Tang et al - Ivermectin, a potential anticancer drug derived from an antiparasitic drug

    2019 Sep Intuyod et al - Anti-parasitic Drug Ivermectin Exhibits Potent Anticancer Activity Against Gemcitabine-resistant Cholangiocarcinoma In Vitro

    2018 Feb - Juarez et al - The multitargeted drug ivermectin: from an antiparasitic agent to a repositioned cancer drug

https://makismd.substack.com/p/ivermectin-and-cancer-it-has-at-least

« Last Edit: December 07, 2023, 08:15:06 AM by admin »
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